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What is Triclabendazole
Triclabendazole is an oral anthelmintic indicated for the treatment of fascioliasis in patients 6 years and older.
It is given as a 2-dose regimen. QT prolongation was noted in animal studies.
Gastrointestinal adverse reactions are common, but may also be secondary to the infection and may be more frequent or severe in patients with a heavy worm burden.
Brand Name
Egaten
Indications
- Fasciola hepatica
- fascioliasis
Side Effects
- abdominal pain
- anorexia
- arthralgia
- asthenia
- back pain
- chest pain (unspecified)
- constipation
- cough
- diarrhea
- dyspnea
- elevated hepatic enzymes
- fever
- headache
- hyperbilirubinemia
- hyperhidrosis
- jaundice
- nausea
- pruritus
- QT prolongation
- urine discoloration
- urticaria
- vertigo
- vomiting
Monitoring Parameters
- ECG
Contraindications
- alcoholism
- bradycardia
- breast-feeding
- cardiac arrhythmias
- cardiac disease
- coronary artery disease
- diabetes mellitus
- females
- geriatric
- hepatic disease
- hypocalcemia
- hypokalemia
- hypomagnesemia
- long QT syndrome
- myocardial infarction
- pregnancy
- QT prolongation
- thyroid disease
Interactions
No information is available regarding drug interactions associated with Triclabendazole
