What's on this Page
What is Tetrahydrozoline
Tetrahydrozoline is an intranasal and ophthalmic topical vasoconstrictor. It is administered intranasally to treat nasal congestion associated with acute or chronic rhinitis, sinusitis, the common cold, and hay fever and other allergies.
The effectiveness of xylometazoline for relieving nasal congestion and its adverse effect profile are similar to other imidazoline derivatives.
Excessive or prolonged nasal use can cause nasal mucosa irritation; nasal use should generally not exceed 3 consecutive days since some degree of rebound congestion usually results.
Tetrahydrozoline is administered ophthalmically to relieve redness of the eye due to minor ocular irritants. This drug was approved by the FDA in 1954.
Br
Indications
- nasal congestion
- xerophthalmia
For the relief of redness of the eye due to minor irritations or relief of burning and irritation due to xerophthalmia or discomfort due to minor irritations or to exposure to wind or sun
Side Effects
- blurred vision
- bradycardia
- coma
- drowsiness
- headache
- hypertension
- hypotension
- hypothermia
- insomnia
- lethargy
- mydriasis
- nasal congestion
- nasal dryness
- nasal irritation
- nausea
- ocular irritation
- ocular pain
- palpitations
- respiratory depression
- rhinitis
- sinus tachycardia
- sneezing
- tremor
- visual impairment
- vomiting
- weakness
Monitoring Parameters
- laboratory monitoring not necessary
Contraindications
- breast-feeding
- children
- closed-angle glaucoma
- contact lenses
- coronary artery disease
- diabetes mellitus
- hypertension
- hyperthyroidism
- infants
- MAOI therapy
- neonates
- pregnancy
Interactions
- Colchicine
- Colchicine; Probenecid
- Linezolid
- Monoamine oxidase inhibitors
- Nafarelin
- Nicotine
- Rasagiline
