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What is Sodium Phosphate Monobasic Monohydrate and Sodium Phosphate Dibasic Anhydrous
Sodium phosphate monobasic monohydrate; sodium phosphate dibasic anhydrous is a combination of sodium phosphate salts used as a laxative for the relief of constipation and as a purgative to evacuate the bowel prior to colonic radiologic examinations or surgery.
Brand Names
- Fleet
- OsmoPrep
- Ready To Use Saline
- Visicol
Indications & Dosage
- bowel preparation
- constipation
- hypophosphatemia
- nutritional supplementation
For use as a bowel evacuant to clean the colon prior to colonoscopy (bowel preparation)
Side Effects
- abdominal pain
- acute phosphate nephropathy
- aluminum toxicity
- anaphylactoid reactions
- angioedema
- arrhythmia exacerbation
- bowel ischemia
- bronchospasm
- colitis
- dehydration
- diarrhea
- dizziness
- dysphagia
- dyspnea
- edema
- fecal incontinence
- fecal urgency
- fluid retention
- headache
- hypernatremia
- hyperphosphatemia
- hypocalcemia
- hypokalemia
- hypotension
- hypovolemia
- injection site reaction
- metabolic acidosis
- muscle cramps
- muscle paralysis
- nausea
- oral ulceration
- paresthesias
- peptic ulcer
- phlebitis
- pruritus
- QT prolongation
- rash
- renal failure (unspecified)
- seizures
- tetany
- urticaria
- vomiting
- weakness
Monitoring Parameters
- ECG
- serum creatinine/BUN
- serum electrolytes
- serum phosphate
Contraindications
- abdominal pain
- acute abdomen
- acute myocardial infarction
- alcoholism
- angina
- appendicitis
- arrhythmia exacerbation
- ascites
- biliary cirrhosis
- breast-feeding
- cardiac arrhythmias
- cardiac disease
- cardiomyopathy
- children
- colitis
- coronary artery bypass graft surgery (CABG)
- dehydration
- edema
- electrolyte imbalance
- esophageal stricture
- gastroparesis
- geriatric
- GI bleeding
- GI obstruction
- GI perforation
- heart failure
- hepatic disease
- hepatitis
- hypernatremia
- hyperphosphatemia
- hypertension
- hypocalcemia
- hypokalemia
- hyponatremia
- hypoparathyroidism
- hypothyroidism
- hypovolemia
- ileus
- infants
- inflammatory bowel disease
- neonates
- nephrotoxicity
- osteomalacia
- pancreatitis
- peripheral edema
- pregnancy
- premature neonates
- pulmonary edema
- QT prolongation
- renal disease
- renal failure
- renal impairment
- scleroderma
- seizure disorder
- seizures
- sodium restriction
- surgery
- toxic megacolon
- ulcerative colitis
- vomiting
Interactions
- Acetaminophen; Aspirin, ASA; Caffeine
- Acetaminophen; Caffeine; Magnesium Salicylate; Phenyltoloxamine
- Aluminum Hydroxide
- Aluminum Hydroxide; Magnesium Carbonate
- Aluminum Hydroxide; Magnesium Hydroxide
- Aluminum Hydroxide; Magnesium Hydroxide; Simethicone
- Aluminum Hydroxide; Magnesium Trisilicate
- Amiloride
- Amiloride; Hydrochlorothiazide, HCTZ
- Angiotensin II receptor antagonists
- Angiotensin-converting enzyme inhibitors
- Antacids
- Aspirin, ASA
- Aspirin, ASA; Butalbital; Caffeine
- Aspirin, ASA; Butalbital; Caffeine; Codeine
- Aspirin, ASA; Caffeine; Dihydrocodeine
- Aspirin, ASA; Caffeine; Orphenadrine
- Aspirin, ASA; Carisoprodol
- Aspirin, ASA; Carisoprodol; Codeine
- Aspirin, ASA; Citric Acid; Sodium Bicarbonate
- Aspirin, ASA; Dipyridamole
- Aspirin, ASA; Omeprazole
- Aspirin, ASA; Oxycodone
- Aspirin, ASA; Pravastatin
- Atropine; Difenoxin
- Atropine; Diphenoxylate
- Azelastine; Fluticasone
- Beclomethasone
- Betamethasone
- Bisacodyl
- Bismuth Subsalicylate
- Bismuth Subsalicylate; Metronidazole; Tetracycline
- Budesonide
- Budesonide; Formoterol
- Bulk-forming laxative
- Burosumab
- Caffeine
- Calcium
- Calcium Acetate
- Calcium Carbonate
- Calcium Carbonate; Magnesium Hydroxide
- Calcium Carbonate; Risedronate
- Calcium Carbonate; Simethicone
- Calcium Chloride
- Calcium Gluconate
- Calcium; Vitamin D
- Carbonic anhydrase inhibitors
- Choline Salicylate; Magnesium Salicylate
- Chromium
- Ciclesonide
- Colchicine
- Colchicine; Probenecid
- Corticosteroids
- Corticotropin, ACTH
- Cortisone
- Deflazacort
- Dexamethasone
- Diazoxide
- Dichlorphenamide
- Erdafitinib
- Fludrocortisone
- Flunisolide
- Fluticasone
- Fluticasone; Salmeterol
- Fluticasone; Umeclidinium; Vilanterol
- Fluticasone; Vilanterol
- Formoterol; Mometasone
- Hetastarch; Dextrose; Electrolytes
- Hydralazine
- Hydralazine; Hydrochlorothiazide, HCTZ
- Hydralazine; Isosorbide Dinitrate, ISDN
- Hydrochlorothiazide, HCTZ; Methyldopa
- Hydrochlorothiazide, HCTZ; Spironolactone
- Hydrochlorothiazide, HCTZ; Triamterene
- Hydrocortisone
- Indapamide
- Lactulose
- Loop diuretics
- Lubiprostone
- Magnesium Citrate
- Magnesium Hydroxide
- Magnesium Salicylate
- Methadone
- Methyldopa
- Methylprednisolone
- Mineral Oil
- Mometasone
- Nonsteroidal antiinflammatory drugs
- Pimozide
- Polyethylene Glycol
- Polyethylene Glycol; Electrolytes
- Polyethylene Glycol; Electrolytes; Ascorbic Acid
- Polyethylene Glycol; Electrolytes; Bisacodyl
- Potassium-sparing diuretics
- Prednisolone
- Prednisone
- Salsalate
- Spironolactone
- Stool Softners
- Thiazide diuretics
- Triamcinolone
- Triamterene
- Trientine
