What's on this Page
What is Semaglutide
Brand Names
- OZEMPIC
- Rybelsus
Indications & Dosage
- reduction of cardiovascular mortality
- type 2 diabetes mellitus
For the treatment of type 2 diabetes mellitus in combination with diet and exercise
Side Effects
- abdominal pain
- antibody formation
- cholelithiasis
- constipation
- dehydration
- diarrhea
- dizziness
- dysgeusia
- dyspepsia
- eructation
- fatigue
- flatulence
- gastritis
- gastroesophageal reflux
- hyperamylasemia
- hypoglycemia
- injection site reaction
- nausea
- new primary malignancy
- pancreatitis
- renal failure (unspecified)
- retinopathy
- vomiting
Monitoring Parameters
- blood glucose
- glycosylated hemoglobin A1c (HbA1c)
Contraindications
- breast-feeding
- burns
- children
- diabetic ketoacidosis
- diabetic retinopathy
- diarrhea
- fever
- geriatric
- history of angioedema
- hypoglycemia
- infants
- infection
- medullary thyroid carcinoma (MTC)
- multiple endocrine neoplasia syndrome type 2 (MEN 2)
- neonates
- pancreatitis
- pregnancy
- renal impairment
- reproductive risk
- serious hypersensitivity reactions or anaphylaxis
- surgery
- thyroid C-cell tumors
- thyroid cancer
- thyroid disease
- trauma
- type 1 diabetes mellitus
- vomiting
Interactions
- Acetaminophen; Aspirin, ASA; Caffeine
- Acetaminophen; Caffeine; Magnesium Salicylate; Phenyltoloxamine
- Acetaminophen; Caffeine; Phenyltoloxamine; Salicylamide
- Acetazolamide
- Aliskiren; Valsartan
- Aminosalicylate sodium, Aminosalicylic acid
- Amlodipine; Benazepril
- Amlodipine; Hydrochlorothiazide, HCTZ; Olmesartan
- Amlodipine; Hydrochlorothiazide, HCTZ; Valsartan
- Amlodipine; Olmesartan
- Amlodipine; Telmisartan
- Amlodipine; Valsartan
- Amoxicillin; Clarithromycin; Lansoprazole
- Amoxicillin; Clarithromycin; Omeprazole
- Amprenavir
- Androgens
- Angiotensin II receptor antagonists
- Angiotensin-converting enzyme inhibitors
- Aspirin, ASA
- Aspirin, ASA; Butalbital; Caffeine
- Aspirin, ASA; Butalbital; Caffeine; Codeine
- Aspirin, ASA; Caffeine; Dihydrocodeine
- Aspirin, ASA; Caffeine; Orphenadrine
- Aspirin, ASA; Carisoprodol
- Aspirin, ASA; Carisoprodol; Codeine
- Aspirin, ASA; Citric Acid; Sodium Bicarbonate
- Aspirin, ASA; Dipyridamole
- Aspirin, ASA; Omeprazole
- Aspirin, ASA; Oxycodone
- Aspirin, ASA; Pravastatin
- Atazanavir
- Atazanavir; Cobicistat
- Atropine; Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
- atypical antipsychotic
- Azilsartan
- Azilsartan; Chlorthalidone
- Benazepril
- Benazepril; Hydrochlorothiazide, HCTZ
- Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
- Beta-blockers
- Bismuth Subsalicylate
- Bismuth Subsalicylate; Metronidazole; Tetracycline
- Bortezomib
- Candesartan
- Candesartan; Hydrochlorothiazide, HCTZ
- Captopril
- Captopril; Hydrochlorothiazide, HCTZ
- Carbamazepine
- Carbonic anhydrase inhibitors
- Chloroquine
- Chlorpromazine
- Chlorthalidone; Clonidine
- Choline Salicylate; Magnesium Salicylate
- Chromium
- Clarithromycin
- Clonidine
- Codeine; Phenylephrine; Promethazine
- Codeine; Promethazine
- Conjugated Estrogens; Medroxyprogesterone
- Corticosteroids
- Cyclosporine
- Daclatasvir
- Danazol
- Darunavir
- Darunavir; Cobicistat
- Darunavir; Cobicistat; Emtricitabine; Tenofovir alafenamide
- Dasabuvir; Ombitasvir; Paritaprevir; Ritonavir
- Dasabuvir; Ombitasvir; Paritaprevir; Ritonavir
- Dextromethorphan; Promethazine
- Diazoxide
- Dienogest; Estradiol valerate
- Digoxin
- Disopyramide
- Drospirenone
- Drospirenone; Estradiol
- Drospirenone; Ethinyl Estradiol
- Drospirenone; Ethinyl Estradiol; Levomefolate
- Elagolix; Estradiol; Norethindrone acetate
- Elbasvir; Grazoprevir
- Enalapril, Enalaprilat
- Enalapril; Felodipine
- Enalapril; Hydrochlorothiazide, HCTZ
- Eprosartan
- Eprosartan; Hydrochlorothiazide, HCTZ
- Esterified Estrogens; Methyltestosterone
- Estradiol Cypionate; Medroxyprogesterone
- Estradiol; Levonorgestrel
- Estradiol; Norethindrone
- Estradiol; Norgestimate
- Estradiol; Progesterone
- Estrogens
- Ethanol
- Ethinyl Estradiol; Desogestrel
- Ethinyl Estradiol; Ethynodiol Diacetate
- Ethinyl Estradiol; Etonogestrel
- Ethinyl Estradiol; Levonorgestrel
- Ethinyl Estradiol; Levonorgestrel; Ferrous bisglycinate
- Ethinyl Estradiol; Levonorgestrel; Folic Acid; Levomefolate
- Ethinyl Estradiol; Norelgestromin
- Ethinyl Estradiol; Norethindrone
- Ethinyl Estradiol; Norethindrone Acetate
- Ethinyl Estradiol; Norethindrone Acetate; Ferrous fumarate
- Ethinyl Estradiol; Norethindrone; Ferrous fumarate
- Ethinyl Estradiol; Norgestimate
- Ethinyl Estradiol; Norgestrel
- Ethotoin
- Etonogestrel
- Fibric acid derivatives
- Fluoxetine
- Fluoxetine; Olanzapine
- Fluoxymesterone
- Fluphenazine
- Fosamprenavir
- Fosinopril
- Fosinopril; Hydrochlorothiazide, HCTZ
- Fosphenytoin
- Garlic, Allium sativum
- Glecaprevir; Pibrentasvir
- Green Tea
- Hydrochlorothiazide, HCTZ; Irbesartan
- Hydrochlorothiazide, HCTZ; Lisinopril
- Hydrochlorothiazide, HCTZ; Losartan
- Hydrochlorothiazide, HCTZ; Moexipril
- Hydrochlorothiazide, HCTZ; Olmesartan
- Hydrochlorothiazide, HCTZ; Quinapril
- Hydrochlorothiazide, HCTZ; Telmisartan
- Hydrochlorothiazide, HCTZ; Triamterene
- Hydrochlorothiazide, HCTZ; Valsartan
- Hydroxychloroquine
- Hydroxyprogesterone
- Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate; Sodium Biphosphate
- Indapamide
- Indinavir
- Irbesartan
- Isocarboxazid
- Lanreotide
- Ledipasvir; Sofosbuvir
- Leuprolide; Norethindrone
- Levonorgestrel
- Levothyroxine
- Levothyroxine; Liothyronine (Porcine)
- Levothyroxine; Liothyronine (Synthetic)
- Linezolid
- Liothyronine
- Lisinopril
- Lithium
- Lomefloxacin
- Loop diuretics
- Lopinavir; Ritonavir
- Lorcaserin
- Losartan
- Lovastatin; Niacin
- Magnesium Salicylate
- Mecasermin rinfabate
- Mecasermin, Recombinant, rh-IGF-1
- Medroxyprogesterone
- Meperidine; Promethazine
- Mesoridazine
- Mestranol; Norethindrone
- Methazolamide
- Methyltestosterone
- Metyrapone
- Moexipril
- Monoamine oxidase inhibitors
- Nandrolone Decanoate
- Nebivolol; Valsartan
- Nelfinavir
- Niacin, Niacinamide
- Niacin; Simvastatin
- Nicotine
- Norethindrone
- Norgestrel
- Octreotide
- Olmesartan
- Ombitasvir; Paritaprevir; Ritonavir
- Orlistat
- Oxandrolone
- Oxymetholone
- Pasireotide
- Pegvisomant
- Pentamidine
- Pentoxifylline
- Perindopril
- Perindopril; Amlodipine
- Perphenazine
- Perphenazine; Amitriptyline
- Phenelzine
- Phenothiazines
- Phenylephrine; Promethazine
- Phenytoin
- Prasterone, Dehydroepiandrosterone, DHEA (Dietary Supplements)
- Prasterone, Dehydroepiandrosterone, DHEA (FDA-approved)
- Prochlorperazine
- Progesterone
- Progestins
- Promethazine
- Protease inhibitors
- Quinapril
- Quinolones
- Ramipril
- Reserpine
- Ritonavir
- Sacubitril; Valsartan
- Salicylates
- Salsalate
- Saquinavir
- Segesterone Acetate; Ethinyl Estradiol
- Selegiline
- Sofosbuvir
- Sofosbuvir; Velpatasvir
- Sofosbuvir; Velpatasvir; Voxilaprevir
- Somatropin, rh-GH
- Sparfloxacin
- Sulfonamides
- Sympathomimetics
- Tacrolimus
- Tegaserod
- Telmisartan
- Testolactone
- Testosterone
- Theophylline, Aminophylline
- Thiazide diuretics
- Thiethylperazine
- Thioridazine
- Thyroid hormones
- Tipranavir
- tobacco
- Trandolapril
- Trandolapril; Verapamil
- Tranylcypromine
- Triamterene
- Trifluoperazine
- Valsartan
- Warfarin
