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What is Rifamycin
Rifamycin is an oral ansamycin class antibacterial drug indicated for treatment of traveler’s diarrhea caused by noninvasive strains of Escherichia coli (E. coli), not complicated by fever or blood in the stool.
Rifamycin is minimally absorbed; therefore, systemic concentrations are generally below the level of detection.
Clinically relevant drug interactions are not expected.
The multi-matrix structure (MMX) technology creates a modified-release formulation that allows rifamycin to be delivered to the distal small bowel and colon without interfering with the normal flora in the upper GI tract.
Brand Name
Aemcolo
Indications
- Escherichia coli
- traveler’s diarrhea
Side Effects
- abdominal pain
- constipation
- dyspepsia
- fever
- headache
- pseudomembranous colitis
Monitoring Parameters
- laboratory monitoring not necessary
Contraindications
- breast-feeding
- colitis
- diarrhea
- fever
- geriatric
- GI bleeding
- GI disease
- inflammatory bowel disease
- pregnancy
- pseudomembranous colitis
- rifamycin hypersensitivity
- ulcerative colitis
Interactions
There are no drug interactions associated with Rifamycin products.
