Psychotropic medications listed on the American Geriatric Society 2012 Updated Beers Criteria

What are some common psychotropic medications or medication classes listed on the American Geriatric Society 2012 Updated Beers Criteria for Potentially Inappropriate Medication Use in Older Adults?

  • Antipsychotics (all antipsychotics carry an FDA black box warning regarding association with increased mortality when used in the elderly with dementia)
  • TCAs (amitriptyline, clomipramine, doxepin, etc.—due to anticholinergic effects)
  • Barbiturates (increased risk of dependence and overdose)
  • Antihistamines, anticholinergics, benzodiazepines, and other sedative hypnotics (cause cognitive impairments, delirium, falls)
  • Bupropion, clozapine, olanzapine, maprotiline (lower seizure threshold)

Sources

  • Ostacher MJ, Hsin H: The Use of antiepileptic drugs in psychiatry. In Stern TA, Fava M, Wilens TE, Rosenbaum JF (eds): Massachusetts General Hospital comprehensive clinical psychiatry. London: Elsevier, 2016, p 536. 
  • Dolder C, Luna B: Psychopharmacology: a pharmacodynamics approach. In Jeste DV, Friedman JH (eds): Psychiatry for neurologists. Totowa, NJ: Humana Press, 2006, p 317. 
  • Freudenreich OD, Goff DC, Henderson DC: Antipsychotics. In Stern TA, Fava M, Wilens TE, Rosenbaum JF (eds): Massachusetts General Hospital comprehensive clinical psychiatry. London: Elsevier, 2016, pp 475-488. 
  • American Geriatrics Society 2012 Beers Criteria Update Expert Panel. American Geriatrics Society updated Beers Criteria for potentially inappropriate medication use in older adults. J Am Geriatr Soc 60(4):616-631, 2012.
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