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Potassium Gluconate Brand Names- Glu-K | Kaon
What is Potassium Gluconate
Potassium is the primary intracellular cation. It plays a major role in muscle and nerve cell electrodynamics. Its concentration inside the cell (roughly 150 to 160 mEq/L) is 25 to 35 times greater than extracellular concentrations.
Hypokalemia is generally defined as a serum potassium concentration less than 3.5 mEq/liter. However, the National Council on Potassium in Clinical Practice recommends that serum potassium concentrations of at least 4 mEq/L be achieved and maintained in patients with hypertension, heart failure, and cardiac arrhythmias.
In addition, the Council recommends potassium supplementation for patients at risk for developing hypokalemia and associated complications (e.g., patients with potential for diuretic-induced potassium loss, patients sensitive to sodium or with high sodium intake, and patients with reduced GI intake or GI disturbances [e.g., vomiting, diarrhea]).
Potassium gluconate is a dietary supplement used to maintain potassium balance (i.e., hypokalemia prevention)
Indications
- hypokalemia prevention
- nutritional supplementation
- Potassium supplement dosing must be individualized according to the needs of the patient. Requirement estimation should be based on clinical condition which includes plasma concentrations and patient response.
- Hypokalemia is generally defined as a serum potassium concentration less than 3.5 mEq/L; however, serum potassium concentrations do not always correlate with cellular potassium levels. The National Council on Potassium in Clinical Practice recommends that serum potassium concentrations of at least 4 mEq/L be achieved and maintained in patients with hypertension, heart failure, and cardiac arrhythmias.
- 90 mg of elemental potassium (2.3 mEq) is provided by 550 mg of potassium gluconate.
Side Effects
- abdominal pain
- anxiety
- arrhythmia exacerbation
- asystole
- AV block
- bradycardia
- cardiac arrest
- confusion
- diarrhea
- dyspnea
- fatigue
- flatulence
- hyperkalemia
- hyporeflexia
- hypotension
- muscle paralysis
- nausea
- paresthesias
- rash
- ventricular fibrillation
- vomiting
- weakness
Monitoring Parameters
- serum creatinine/BUN
- serum potassium
Contraindications
- adrenal insufficiency
- atrial fibrillation
- atrial flutter
- AV block
- breast-feeding
- burns
- cardiac arrhythmias
- dehydration
- diabetic ketoacidosis
- digitalis toxicity
- geriatric
- heart failure
- hyperkalemia
- metabolic acidosis
- muscle channelopathy
- pregnancy
- renal disease
- renal failure
- renal impairment
- ventricular arrhythmias
- ventricular fibrillation
- ventricular tachycardia
Interactions
- Aliskiren
- Aliskiren; Amlodipine
- Aliskiren; Amlodipine; Hydrochlorothiazide, HCTZ
- Aliskiren; Hydrochlorothiazide, HCTZ
- Aliskiren; Valsartan
- Amiloride
- Amiloride; Hydrochlorothiazide, HCTZ
- Amlodipine; Benazepril
- Amlodipine; Celecoxib
- Amlodipine; Hydrochlorothiazide, HCTZ; Olmesartan
- Amlodipine; Hydrochlorothiazide, HCTZ; Valsartan
- Amlodipine; Olmesartan
- Amlodipine; Telmisartan
- Amlodipine; Valsartan
- Ammonium Chloride
- Angiotensin II receptor antagonists
- Angiotensin-converting enzyme inhibitors
- Anticholinergics
- Atropine
- Atropine; Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
- Atropine; Difenoxin
- Atropine; Diphenoxylate
- Atropine; Edrophonium
- Atropine; Hyoscyamine; Phenobarbital; Scopolamine
- Azelastine; Fluticasone
- Azilsartan
- Azilsartan; Chlorthalidone
- Beclomethasone
- Belladonna Alkaloids; Ergotamine; Phenobarbital
- Belladonna; Opium
- Benazepril
- Benazepril; Hydrochlorothiazide, HCTZ
- Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
- Benztropine
- Betamethasone
- Budesonide
- Budesonide; Formoterol
- Candesartan
- Candesartan; Hydrochlorothiazide, HCTZ
- Captopril
- Captopril; Hydrochlorothiazide, HCTZ
- Celecoxib
- Chlordiazepoxide; Clidinium
- Ciclesonide
- Corticosteroids
- Cortisone
- Cyclosporine
- Deflazacort
- Dexamethasone
- Diclofenac
- Diclofenac; Misoprostol
- Dicyclomine
- Diflunisal
- Digoxin
- Diphenhydramine; Ibuprofen
- Diphenhydramine; Naproxen
- Drospirenone
- Drospirenone; Estradiol
- Drospirenone; Ethinyl Estradiol
- Drospirenone; Ethinyl Estradiol; Levomefolate
- Enalapril, Enalaprilat
- Enalapril; Felodipine
- Enalapril; Hydrochlorothiazide, HCTZ
- Eplerenone
- Eprosartan
- Eprosartan; Hydrochlorothiazide, HCTZ
- Esomeprazole; Naproxen
- Ethanol
- Etodolac
- Famotidine; Ibuprofen
- Fenoprofen
- Flavoxate
- Fludrocortisone
- Flunisolide
- Flurbiprofen
- Fluticasone
- Fluticasone; Salmeterol
- Fluticasone; Umeclidinium; Vilanterol
- Fluticasone; Vilanterol
- food
- Formoterol; Mometasone
- Fosinopril
- Fosinopril; Hydrochlorothiazide, HCTZ
- Glycopyrrolate
- Glycopyrrolate; Formoterol
- Heparin
- Homatropine; Hydrocodone
- Hydrochlorothiazide, HCTZ; Irbesartan
- Hydrochlorothiazide, HCTZ; Lisinopril
- Hydrochlorothiazide, HCTZ; Losartan
- Hydrochlorothiazide, HCTZ; Moexipril
- Hydrochlorothiazide, HCTZ; Olmesartan
- Hydrochlorothiazide, HCTZ; Quinapril
- Hydrochlorothiazide, HCTZ; Spironolactone
- Hydrochlorothiazide, HCTZ; Telmisartan
- Hydrochlorothiazide, HCTZ; Triamterene
- Hydrochlorothiazide, HCTZ; Valsartan
- Hydrocodone; Ibuprofen
- Hydrocortisone
- Hyoscyamine
- Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate; Sodium Biphosphate
- Ibuprofen
- Ibuprofen; Oxycodone
- Ibuprofen; Pseudoephedrine
- Indacaterol; Glycopyrrolate
- Indomethacin
- Irbesartan
- Ketoprofen
- Ketorolac
- Lansoprazole; Naproxen
- Lisinopril
- Loperamide
- Loperamide; Simethicone
- Losartan
- Meclofenamate Sodium
- Mefenamic Acid
- Meloxicam
- Mepenzolate
- Methenamine; Sodium Acid Phosphate; Methylene Blue; Hyoscyamine
- Methscopolamine
- Methylprednisolone
- Moexipril
- Mometasone
- Nabumetone
- Naproxen
- Naproxen; Pseudoephedrine
- Naproxen; Sumatriptan
- Nebivolol; Valsartan
- Nonsteroidal antiinflammatory drugs
- Olmesartan
- Oxaprozin
- Oxybutynin
- Penicillin G
- Perindopril
- Perindopril; Amlodipine
- Piroxicam
- Prednisolone
- Prednisone
- Propantheline
- Quinapril
- Ramipril
- Rofecoxib
- Sacubitril; Valsartan
- Scopolamine
- Sodium Polystyrene Sulfonate
- Spironolactone
- Sulfamethoxazole; Trimethoprim, SMX-TMP, Cotrimoxazole
- Sulindac
- Tacrolimus
- Telmisartan
- Tolmetin
- Trandolapril
- Trandolapril; Verapamil
- Triamcinolone
- Triamterene
- Trientine
- Trihexyphenidyl
- Trimethoprim
- Valdecoxib
- Valsartan
