Potassium Bicarbonate

Potassium Bicarbonate Brand Names

Effer-K | K Plus Care ET | Klor-Con EF | Klorvess | K-Lyte | K-Lyte DS | K-Vescent

What is Potassium Bicarbonate

Potassium bicarbonate is recommended when potassium depletion occurs in the setting of metabolic acidosis (pH less than 7.4)

Potassium is the primary intracellular cation. It plays a major role in muscle and nerve cell electrodynamics. Its concentration inside the cell (roughly 150 to 160 mEq/L) is 25 to 35 times greater than extracellular concentrations.

Hypokalemia is generally defined as a serum potassium concentration less than 3.5 mEq/liter. However, the National Council on Potassium in Clinical Practice recommends that serum potassium concentrations of at least 4 mEq/L be achieved and maintained in patients with hypertension, heart failure, and cardiac arrhythmias.

In addition, the Council recommends potassium supplementation for patients at risk for developing hypokalemia and associated complications (e.g., patients with potential for diuretic-induced potassium loss, patients sensitive to sodium or with high sodium intake, and patients with reduced GI intake or GI disturbances [e.g., vomiting, diarrhea]).

Indications

1. hypokalemia
2. hypokalemia prevention
3. nutritional supplementation

Side Effects

1. abdominal pain
2. anxiety
3. arrhythmia exacerbation
4. asystole
5. AV block
6. bradycardia
7. cardiac arrest
8. confusion
9. diarrhea
10. dyspnea
11. fatigue
12. flatulence
13. hyperkalemia
14. hyporeflexia
15. hypotension
16. muscle paralysis
17. nausea
18. paresthesias
19. rash
20. ventricular fibrillation
21. vomiting
22. weakness

Monitoring Parameters

• serum bicarbonate
• serum chloride
• serum creatinine/BUN
• serum potassium

Contraindications

• adrenal insufficiency
• atrial fibrillation
• atrial flutter
• AV block
• breast-feeding
• burns
• cardiac arrhythmias
• dehydration
• diabetic ketoacidosis
• digitalis toxicity
• geriatric
• heart failure
• hyperkalemia
• metabolic acidosis
• muscle channelopathy
• pregnancy
• renal disease
• renal failure
• renal impairment
• ventricular arrhythmias
• ventricular fibrillation
• ventricular tachycardia

Interactions

• Acetaminophen; Aspirin, ASA; Caffeine
• Acetaminophen; Caffeine; Magnesium Salicylate; Phenyltoloxamine
• Acetaminophen; Caffeine; Phenyltoloxamine; Salicylamide
• Acetaminophen; Chlorpheniramine; Dextromethorphan; Pseudoephedrine
• Acetaminophen; Dextromethorphan; Pseudoephedrine
• Acetaminophen; Pseudoephedrine
• Acrivastine; Pseudoephedrine
• Aliskiren
• Aliskiren; Amlodipine
• Aliskiren; Amlodipine; Hydrochlorothiazide, HCTZ
• Aliskiren; Hydrochlorothiazide, HCTZ
• Aliskiren; Valsartan
• Aluminum Hydroxide
• Aluminum Hydroxide; Magnesium Carbonate
• Aluminum Hydroxide; Magnesium Hydroxide
• Aluminum Hydroxide; Magnesium Hydroxide; Simethicone
• Aluminum Hydroxide; Magnesium Trisilicate
• Amiloride
• Amiloride; Hydrochlorothiazide, HCTZ
• Aminosalicylate sodium, Aminosalicylic acid
• Amlodipine; Benazepril
• Amlodipine; Celecoxib
• Amlodipine; Hydrochlorothiazide, HCTZ; Olmesartan
• Amlodipine; Hydrochlorothiazide, HCTZ; Valsartan
• Amlodipine; Olmesartan
• Amlodipine; Telmisartan
• Amlodipine; Valsartan
• Ammonium Chloride
• Amphetamines
• Angiotensin II receptor antagonists
• Angiotensin-converting enzyme inhibitors
• Anticholinergics
• Aspirin, ASA
• Aspirin, ASA; Butalbital; Caffeine
• Aspirin, ASA; Butalbital; Caffeine; Codeine
• Aspirin, ASA; Caffeine; Dihydrocodeine
• Aspirin, ASA; Caffeine; Orphenadrine
• Aspirin, ASA; Carisoprodol
• Aspirin, ASA; Carisoprodol; Codeine
• Aspirin, ASA; Citric Acid; Sodium Bicarbonate
• Aspirin, ASA; Dipyridamole
• Aspirin, ASA; Omeprazole
• Aspirin, ASA; Oxycodone
• Aspirin, ASA; Pravastatin
• Atropine
• Atropine; Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
• Atropine; Difenoxin
• Atropine; Diphenoxylate
• Atropine; Edrophonium
• Atropine; Hyoscyamine; Phenobarbital; Scopolamine
• Azelastine; Fluticasone
• Azilsartan
• Azilsartan; Chlorthalidone
• Beclomethasone
• Belladonna Alkaloids; Ergotamine; Phenobarbital
• Belladonna; Opium
• Benazepril
• Benazepril; Hydrochlorothiazide, HCTZ
• Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
• Benzphetamine
• Benztropine
• Betamethasone
• Bismuth Subsalicylate
• Bismuth Subsalicylate; Metronidazole; Tetracycline
• Brompheniramine; Hydrocodone; Pseudoephedrine
• Brompheniramine; Pseudoephedrine
• Budesonide
• Budesonide; Formoterol
• Budesonide; Glycopyrrolate; Formoterol
• Calcium Carbonate
• Calcium Carbonate; Magnesium Hydroxide
• Calcium Carbonate; Risedronate
• Calcium Carbonate; Simethicone
• Candesartan
• Candesartan; Hydrochlorothiazide, HCTZ
• Captopril
• Captopril; Hydrochlorothiazide, HCTZ
• Carbetapentane; Pseudoephedrine
• Carbinoxamine; Dextromethorphan; Pseudoephedrine
• Carbinoxamine; Hydrocodone; Pseudoephedrine
• Carbinoxamine; Pseudoephedrine
• Celecoxib
• Cetirizine; Pseudoephedrine
• Chlophedianol; Dexchlorpheniramine; Pseudoephedrine
• Chlordiazepoxide; Clidinium
• Chlorpheniramine; Dihydrocodeine; Pseudoephedrine
• Chlorpheniramine; Guaifenesin; Hydrocodone; Pseudoephedrine
• Chlorpheniramine; Hydrocodone; Pseudoephedrine
• Chlorpheniramine; Pseudoephedrine
• Chlorpropamide
• Choline Salicylate; Magnesium Salicylate
• Ciclesonide
• Colchicine
• Colchicine; Probenecid
• Corticosteroids
• Cortisone
• Cyclosporine
• Deflazacort
• Desloratadine; Pseudoephedrine
• Dexamethasone
• Dexchlorpheniramine; Dextromethorphan; Pseudoephedrine
• Dextromethorphan; Guaifenesin; Pseudoephedrine
• Dextromethorphan; Quinidine
• Diclofenac
• Diclofenac; Misoprostol
• Dicyclomine
• Diflunisal
• Digoxin
• Dihydrocodeine; Guaifenesin; Pseudoephedrine
• Diphenhydramine; Ibuprofen
• Diphenhydramine; Naproxen
• Donepezil; Memantine
• Drospirenone
• Drospirenone; Estradiol
• Drospirenone; Ethinyl Estradiol
• Drospirenone; Ethinyl Estradiol; Levomefolate
• Enalapril, Enalaprilat
• Enalapril; Felodipine
• Enalapril; Hydrochlorothiazide, HCTZ
• Ephedrine
• Eplerenone
• Eprosartan
• Eprosartan; Hydrochlorothiazide, HCTZ
• Esomeprazole; Naproxen
• Etodolac
• Famotidine; Ibuprofen
• Fenoprofen
• Fexofenadine; Pseudoephedrine
• Flavoxate
• Flecainide
• Fludrocortisone
• Flunisolide
• Flurbiprofen
• Fluticasone
• Fluticasone; Salmeterol
• Fluticasone; Umeclidinium; Vilanterol
• Fluticasone; Vilanterol
• food
• Formoterol; Mometasone
• Fosinopril
• Fosinopril; Hydrochlorothiazide, HCTZ
• Glycopyrrolate
• Glycopyrrolate; Formoterol
• Guaifenesin; Hydrocodone; Pseudoephedrine
• Guaifenesin; Pseudoephedrine
• Heparin
• Homatropine; Hydrocodone
• Hydrochlorothiazide, HCTZ; Irbesartan
• Hydrochlorothiazide, HCTZ; Lisinopril
• Hydrochlorothiazide, HCTZ; Losartan
• Hydrochlorothiazide, HCTZ; Moexipril
• Hydrochlorothiazide, HCTZ; Olmesartan
• Hydrochlorothiazide, HCTZ; Quinapril
• Hydrochlorothiazide, HCTZ; Spironolactone
• Hydrochlorothiazide, HCTZ; Telmisartan
• Hydrochlorothiazide, HCTZ; Triamterene
• Hydrochlorothiazide, HCTZ; Valsartan
• Hydrocodone; Ibuprofen
• Hydrocodone; Potassium Guaiacolsulfonate; Pseudoephedrine
• Hydrocodone; Pseudoephedrine
• Hydrocortisone
• Hyoscyamine
• Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate; Sodium Biphosphate
• Ibuprofen
• Ibuprofen; Oxycodone
• Ibuprofen; Pseudoephedrine
• Indacaterol; Glycopyrrolate
• Indomethacin
• Irbesartan
• Ketoprofen
• Ketorolac
• Lansoprazole; Naproxen
• Lisdexamfetamine
• Lisinopril
• Lithium
• Loperamide
• Loperamide; Simethicone
• Loratadine; Pseudoephedrine
• Losartan
• Magnesium Salicylate
• Meclofenamate Sodium
• Mefenamic Acid
• Meloxicam
• Memantine
• Mepenzolate
• Methamphetamine
• Methenamine
• Methenamine; Sodium Acid Phosphate
• Methenamine; Sodium Acid Phosphate; Methylene Blue; Hyoscyamine
• Methscopolamine
• Methylprednisolone
• Moexipril
• Mometasone
• Nabumetone
• Naproxen
• Naproxen; Pseudoephedrine
• Naproxen; Sumatriptan
• Nebivolol; Valsartan
• Nonsteroidal antiinflammatory drugs
• Olmesartan
• Oxaprozin
• Oxybutynin
• Penicillin G
• Perindopril
• Perindopril; Amlodipine
• Piroxicam
• Prednisolone
• Prednisone
• Propantheline
• Pseudoephedrine
• Quinapril
• Quinidine
• Quinine
• Ramipril
• Rofecoxib
• Sacubitril; Valsartan
• Salicylates
• Salsalate
• Scopolamine
• Sodium Polystyrene Sulfonate
• Spironolactone
• Sulfamethoxazole; Trimethoprim, SMX-TMP, Cotrimoxazole
• Sulindac
• Tacrolimus
• Telmisartan
• Tolmetin
• Trandolapril
• Trandolapril; Verapamil
• Triamcinolone
• Triamterene
• Trientine
• Trihexyphenidyl
• Trimethoprim
• Valdecoxib
• Valsartan