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Pirbuterol Brand Names- Maxair | Maxair Autohaler
What is Pirbuterol
Pirbuterol is an inhaled sympathomimetic bronchodilator agent. It is a relatively selective beta-2 receptor agonist and is structurally similar to albuterol.
Pirbuterol is used to prevent or relieve reversible bronchospasm associated with acute and chronic bronchial asthma, exercise-induced bronchospasm, bronchitis, emphysema, bronchiectasis, or other obstructive pulmonary diseases.
Orally inhaled short-acting beta-2 agonists (SABAs) are considered the preferred pharmacologic treatment to relieve acute bronchospasm according to the 2007 guidelines of the Expert Panel of the National Asthma Education and Prevention Program.
In general, if an SABA is required more than 2 days a week or significant symptoms recur, the Panel recommends initiating treatment for persistent asthma (e.g., inhaled corticosteroids).
Quick-relief medication such as SABAs should be made available to all patients with persistent asthma for acute symptom control.
Pirbuterol was approved by the FDA in 1986.
Indications
- acute bronchospasm
- asthma
- bronchiectasis
- bronchospasm prophylaxis
- chronic bronchitis
- chronic obstructive pulmonary disease (COPD)
- emphysema
- exercise-induced bronchospasm prophylaxis
For the treatment of acute bronchospasm or for bronchospasm prophylaxis
Side Effects
- abdominal pain
- alopecia
- anorexia
- anxiety
- arrhythmia exacerbation
- chest pain (unspecified)
- confusion
- cough
- depression
- diarrhea
- dizziness
- dysgeusia
- dysosmia
- edema
- fatigue
- flushing
- glossitis
- headache
- hyperkinesis
- hypertension
- hypokalemia
- hypotension
- insomnia
- nausea
- palpitations
- paresthesias
- pruritus
- QT prolongation
- rash
- restlessness
- sinus tachycardia
- stomatitis
- syncope
- throat irritation
- tremor
- vomiting
- weakness
- weight gain
- xerostomia
Monitoring Parameters
- pulmonary function tests (PFTs)
Contraindications
- AV block
- breast-feeding
- cardiac arrhythmias
- cardiac disease
- children
- coronary artery disease
- deterioration of asthma
- diabetes mellitus
- digitalis toxicity
- geriatric
- glaucoma
- hypertension
- hyperthyroidism
- hypokalemia
- infants
- labor
- MAOI therapy
- neonates
- paradoxical bronchospasm
- pheochromocytoma
- pregnancy
- QT prolongation
- seizure disorder
- seizures
- shock
- tachycardia
- thyroid disease
- thyrotoxicosis
- torsade de pointes
Interactions
- Abarelix
- Acebutolol
- Acetaminophen; Aspirin, ASA; Caffeine
- Acetaminophen; Butalbital; Caffeine
- Acetaminophen; Butalbital; Caffeine; Codeine
- Acetaminophen; Caffeine
- Acetaminophen; Caffeine; Dihydrocodeine
- Acetaminophen; Caffeine; Magnesium Salicylate; Phenyltoloxamine
- Acetaminophen; Caffeine; Phenyltoloxamine; Salicylamide
- Acetaminophen; Chlorpheniramine; Dextromethorphan; Phenylephrine
- Acetaminophen; Chlorpheniramine; Dextromethorphan; Pseudoephedrine
- Acetaminophen; Chlorpheniramine; Phenylephrine; Phenyltoloxamine
- Acetaminophen; Dextromethorphan; Guaifenesin; Phenylephrine
- Acetaminophen; Dextromethorphan; Phenylephrine
- Acetaminophen; Dextromethorphan; Pseudoephedrine
- Acetaminophen; Dichloralphenazone; Isometheptene
- Acetaminophen; Guaifenesin; Phenylephrine
- Acetaminophen; Pseudoephedrine
- Acrivastine; Pseudoephedrine
- Alfuzosin
- Amiodarone
- Amitriptyline
- Amitriptyline; Chlordiazepoxide
- Amoxicillin; Clarithromycin; Lansoprazole
- Amoxicillin; Clarithromycin; Omeprazole
- Amphetamine
- Amphetamine; Dextroamphetamine
- Amphetamine; Dextroamphetamine Salts
- Anagrelide
- Apomorphine
- Aripiprazole
- Arsenic Trioxide
- Artemether; Lumefantrine
- Articaine; Epinephrine
- Asenapine
- Aspirin, ASA; Butalbital; Caffeine
- Aspirin, ASA; Butalbital; Caffeine; Codeine
- Aspirin, ASA; Caffeine; Dihydrocodeine
- Aspirin, ASA; Caffeine; Orphenadrine
- Atenolol
- Atenolol; Chlorthalidone
- Atomoxetine
- Azithromycin
- Bedaquiline
- Bendroflumethiazide; Nadolol
- Benzphetamine
- Beta-adrenergic blockers
- Betaxolol
- Bismuth Subcitrate Potassium; Metronidazole; Tetracycline
- Bismuth Subsalicylate; Metronidazole; Tetracycline
- Bisoprolol
- Bisoprolol; Hydrochlorothiazide, HCTZ
- Brimonidine; Timolol
- Brompheniramine; Carbetapentane; Phenylephrine
- Brompheniramine; Dextromethorphan; Phenylephrine
- Brompheniramine; Hydrocodone; Pseudoephedrine
- Brompheniramine; Pseudoephedrine
- Bumetanide
- Buprenorphine
- Buprenorphine; Naloxone
- Caffeine
- Caffeine; Ergotamine
- Carbetapentane; Chlorpheniramine; Phenylephrine
- Carbetapentane; Diphenhydramine; Phenylephrine
- Carbetapentane; Guaifenesin; Phenylephrine
- Carbetapentane; Phenylephrine
- Carbetapentane; Phenylephrine; Pyrilamine
- Carbetapentane; Pseudoephedrine
- Carbinoxamine; Dextromethorphan; Pseudoephedrine
- Carbinoxamine; Hydrocodone; Phenylephrine
- Carbinoxamine; Hydrocodone; Pseudoephedrine
- Carbinoxamine; Phenylephrine
- Carbinoxamine; Pseudoephedrine
- Carteolol
- Carvedilol
- Ceritinib
- Cetirizine; Pseudoephedrine
- Chlophedianol; Dexchlorpheniramine; Pseudoephedrine
- Chlophedianol; Guaifenesin; Phenylephrine
- Chloroquine
- Chlorpheniramine; Dextromethorphan; Phenylephrine
- Chlorpheniramine; Dihydrocodeine; Phenylephrine
- Chlorpheniramine; Dihydrocodeine; Pseudoephedrine
- Chlorpheniramine; Guaifenesin; Hydrocodone; Pseudoephedrine
- Chlorpheniramine; Hydrocodone; Phenylephrine
- Chlorpheniramine; Hydrocodone; Pseudoephedrine
- Chlorpheniramine; Phenylephrine
- Chlorpheniramine; Pseudoephedrine
- Chlorpromazine
- Ciprofloxacin
- Cisapride
- Citalopram
- Clarithromycin
- Clofazimine
- Clomipramine
- Clozapine
- Cocaine
- Codeine; Phenylephrine; Promethazine
- Codeine; Promethazine
- Crizotinib
- Dasatinib
- Degarelix
- Desipramine
- Desloratadine; Pseudoephedrine
- Deutetrabenazine
- Dexchlorpheniramine; Dextromethorphan; Pseudoephedrine
- Dextroamphetamine
- Dextromethorphan; Diphenhydramine; Phenylephrine
- Dextromethorphan; Guaifenesin; Phenylephrine
- Dextromethorphan; Guaifenesin; Pseudoephedrine
- Dextromethorphan; Promethazine
- Dextromethorphan; Quinidine
- Diethylpropion
- Dihydrocodeine; Guaifenesin; Pseudoephedrine
- Diphenhydramine; Hydrocodone; Phenylephrine
- Diphenhydramine; Phenylephrine
- Disopyramide
- Dobutamine
- Dofetilide
- Dolasetron
- Dolutegravir; Rilpivirine
- Donepezil
- Donepezil; Memantine
- Dopamine
- Dorzolamide; Timolol
- Doxepin
- Dronedarone
- Droperidol
- Efavirenz
- Efavirenz; Emtricitabine; Tenofovir
- Efavirenz; Lamivudine; Tenofovir Disoproxil Fumarate
- Eliglustat
- Emtricitabine; Rilpivirine; Tenofovir alafenamide
- Emtricitabine; Rilpivirine; Tenofovir disoproxil fumarate
- Encorafenib
- Enflurane
- Entrectinib
- Ephedrine
- Epinephrine
- Eribulin
- Erythromycin
- Erythromycin; Sulfisoxazole
- Escitalopram
- Esmolol
- Ethacrynic Acid
- Ezogabine
- Fexofenadine; Pseudoephedrine
- Fingolimod
- Flecainide
- Fluconazole
- Fluoxetine
- Fluoxetine; Olanzapine
- Fluphenazine
- Fluvoxamine
- Foscarnet
- Fostemsavir
- Furosemide
- Gemifloxacin
- Gemtuzumab Ozogamicin
- Gilteritinib
- Glasdegib
- Goserelin
- Granisetron
- Green Tea
- Guaifenesin; Hydrocodone; Pseudoephedrine
- Guaifenesin; Phenylephrine
- Guaifenesin; Pseudoephedrine
- Halofantrine
- Haloperidol
- Halothane
- Histrelin
- Hydrochlorothiazide, HCTZ; Metoprolol
- Hydrochlorothiazide, HCTZ; Propranolol
- Hydrocodone; Phenylephrine
- Hydrocodone; Potassium Guaiacolsulfonate; Pseudoephedrine
- Hydrocodone; Pseudoephedrine
- Hydroxychloroquine
- Hydroxyzine
- Ibuprofen; Pseudoephedrine
- Ibutilide
- Iloperidone
- Imipramine
- Inotuzumab Ozogamicin
- Isocarboxazid
- Isoflurane
- Isoproterenol
- Itraconazole
- Ivosidenib
- Ketoconazole
- Labetalol
- Lapatinib
- Lefamulin
- Lenvatinib
- Leuprolide
- Leuprolide; Norethindrone
- Levobetaxolol
- Levobunolol
- Levofloxacin
- Levomethadyl
- Levothyroxine
- Levothyroxine; Liothyronine (Porcine)
- Levothyroxine; Liothyronine (Synthetic)
- Linezolid
- Liothyronine
- Lithium
- Lofexidine
- Lomefloxacin
- Loop diuretics
- Loperamide
- Loperamide; Simethicone
- Lopinavir; Ritonavir
- Loratadine; Pseudoephedrine
- Macimorelin
- Maprotiline
- Mefloquine
- Meperidine; Promethazine
- Mesoridazine
- Methacholine
- Methadone
- Methamphetamine
- Metoprolol
- Metronidazole
- Midodrine
- Midostaurin
- Mifepristone
- Mirtazapine
- Monoamine oxidase inhibitors
- Moxifloxacin
- Nadolol
- Naproxen; Pseudoephedrine
- Nebivolol
- Nebivolol; Valsartan
- Nilotinib
- Norepinephrine
- Norfloxacin
- Nortriptyline
- Octreotide
- Ofloxacin
- Olanzapine
- Ondansetron
- Osilodrostat
- Osimertinib
- Oxaliplatin
- Ozanimod
- Paliperidone
- Panobinostat
- Pasireotide
- Pazopanib
- Penbutolol
- Pentamidine
- Perphenazine
- Perphenazine; Amitriptyline
- Phendimetrazine
- Phenelzine
- Phentermine
- Phentermine; Topiramate
- Phenylephrine
- Phenylephrine; Promethazine
- Pimavanserin
- Pimozide
- Pindolol
- Pitolisant
- Posaconazole
- Prilocaine; Epinephrine
- Primaquine
- Procainamide
- Procarbazine
- Prochlorperazine
- Promethazine
- Propafenone
- Propranolol
- Protriptyline
- Pseudoephedrine
- Quetiapine
- Quinidine
- Quinine
- Racepinephrine
- Ranolazine
- Rasagiline
- Ribociclib
- Ribociclib; Letrozole
- Rilpivirine
- Risperidone
- Romidepsin
- Saquinavir
- Selpercatinib
- Sertraline
- Sevoflurane
- Siponimod
- Solifenacin
- Sorafenib
- Sotalol
- Sunitinib
- Tacrolimus
- Tamoxifen
- Telavancin
- Telithromycin
- Tetrabenazine
- Theophylline, Aminophylline
- Thiazide diuretics
- Thioridazine
- Thyroid hormones
- Timolol
- Tolterodine
- Toremifene
- Torsemide
- Tranylcypromine
- Trazodone
- Triclabendazole
- Tricyclic antidepressants
- Trifluoperazine
- Trimipramine
- Triptorelin
- Vandetanib
- Vardenafil
- Vemurafenib
- Venlafaxine
- Voriconazole
- Vorinostat
- Ziprasidone
