Phentermine

Phentermine Brand Names

Adipex-P | Atti-Plex P | Atti-Plex P Spansule | Fastin | Ionamin | Lomaira | Pro-Fast | Suprenza | Tara-8

What is Phentermine

Phentermine is an oral, centrally-acting stimulant and sympathomimetic amine.

Phentermine is used as an adjunct to lifestyle modifications for the short-term treatment (i.e., a few weeks) of exogenous obesity in adults and adolescents 17 years and older with a BMI 30 kg/m2 or more or with a BMI of 27 kg/m2 or more in the presence of at least 1 other weight-related risk factor (e.g., controlled hypertension, diabetes mellitus, or dyslipidemia).

Indications

  • obesity

For the short-term (i.e., a few weeks) treatment of exogenous obesity

Side Effects

  1. angina
  2. cardiac valvulopathy
  3. constipation
  4. diarrhea
  5. dizziness
  6. dysgeusia
  7. dysphoria
  8. dyspnea
  9. euphoria
  10. headache
  11. hypertension
  12. impotence (erectile dysfunction)
  13. insomnia
  14. libido decrease
  15. libido increase
  16. nausea
  17. palpitations
  18. peripheral edema
  19. physiological dependence
  20. psychological dependence
  21. psychosis
  22. pulmonary hypertension
  23. restlessness
  24. sinus tachycardia
  25. syncope
  26. tolerance
  27. tremor
  28. urticaria
  29. withdrawal
  30. xerostomia

Monitoring Parameters

  • weight

Contraindications

  • abrupt discontinuation
  • angina
  • anorexia nervosa
  • anxiety
  • breast-feeding
  • cardiac arrhythmias
  • cardiac disease
  • children
  • closed-angle glaucoma
  • coronary artery disease
  • diabetes mellitus
  • dialysis
  • driving or operating machinery
  • ethanol ingestion
  • geriatric
  • heart failure
  • hypertension
  • hyperthyroidism
  • infants
  • insomnia
  • mania
  • MAOI therapy
  • pregnancy
  • psychosis
  • pulmonary hypertension
  • renal disease
  • renal failure
  • renal impairment
  • schizophrenia
  • stroke
  • substance abuse
  • surgery
  • thyroid disease
  • valvular heart disease

Phentermine is contraindicated for use in any patient with a prior history of sympathomimetic amine hypersensitivity or idiosyncratic reaction to sympathomimetic amines.

Interactions

  • Acarbose
  • Acebutolol
  • Acetaminophen; Aspirin, ASA; Caffeine
  • Acetaminophen; Butalbital; Caffeine
  • Acetaminophen; Butalbital; Caffeine; Codeine
  • Acetaminophen; Caffeine
  • Acetaminophen; Caffeine; Dihydrocodeine
  • Acetaminophen; Caffeine; Magnesium Salicylate; Phenyltoloxamine
  • Acetaminophen; Caffeine; Phenyltoloxamine; Salicylamide
  • Acetaminophen; Chlorpheniramine; Dextromethorphan; Phenylephrine
  • Acetaminophen; Chlorpheniramine; Phenylephrine; Phenyltoloxamine
  • Acetaminophen; Dextromethorphan; Guaifenesin; Phenylephrine
  • Acetaminophen; Dextromethorphan; Phenylephrine
  • Acetaminophen; Guaifenesin; Phenylephrine
  • Aclidinium; Formoterol
  • Albiglutide
  • Albuterol
  • Albuterol; Ipratropium
  • Aliskiren; Amlodipine; Hydrochlorothiazide, HCTZ
  • Aliskiren; Hydrochlorothiazide, HCTZ
  • Alogliptin; Pioglitazone
  • Alpha-blockers
  • Alpha-glucosidase Inhibitors
  • Ambrisentan
  • Amifampridine
  • Amiloride; Hydrochlorothiazide, HCTZ
  • Amitriptyline
  • Amitriptyline; Chlordiazepoxide
  • Amlodipine; Hydrochlorothiazide, HCTZ; Olmesartan
  • Amlodipine; Hydrochlorothiazide, HCTZ; Valsartan
  • Amoxapine
  • Amphetamine
  • Amphetamine; Dextroamphetamine
  • Amphetamines
  • Arformoterol
  • Aspirin, ASA; Butalbital; Caffeine
  • Aspirin, ASA; Butalbital; Caffeine; Codeine
  • Aspirin, ASA; Caffeine; Dihydrocodeine
  • Aspirin, ASA; Caffeine; Orphenadrine
  • Atenolol
  • Atenolol; Chlorthalidone
  • Atomoxetine
  • Azilsartan; Chlorthalidone
  • Belladonna Alkaloids; Ergotamine; Phenobarbital
  • Benazepril; Hydrochlorothiazide, HCTZ
  • Bendroflumethiazide; Nadolol
  • Benzphetamine
  • Beta-blockers
  • Betaxolol
  • Bethanechol
  • Bisoprolol
  • Bisoprolol; Hydrochlorothiazide, HCTZ
  • Bosentan
  • Bretylium
  • Brimonidine; Timolol
  • Bromocriptine
  • Brompheniramine; Carbetapentane; Phenylephrine
  • Brompheniramine; Dextromethorphan; Phenylephrine
  • Budesonide; Formoterol
  • Bupropion
  • Bupropion; Naltrexone
  • Caffeine
  • Caffeine; Ergotamine
  • Canagliflozin
  • Canagliflozin; Metformin
  • Candesartan; Hydrochlorothiazide, HCTZ
  • Captopril; Hydrochlorothiazide, HCTZ
  • Carbetapentane; Chlorpheniramine; Phenylephrine
  • Carbetapentane; Diphenhydramine; Phenylephrine
  • Carbetapentane; Guaifenesin; Phenylephrine
  • Carbetapentane; Phenylephrine
  • Carbetapentane; Phenylephrine; Pyrilamine
  • Carbinoxamine; Hydrocodone; Phenylephrine
  • Carbinoxamine; Phenylephrine
  • Cardiac glycosides
  • Carteolol
  • Carvedilol
  • Chlophedianol; Guaifenesin; Phenylephrine
  • Chlorothiazide
  • Chlorpheniramine; Dextromethorphan; Phenylephrine
  • Chlorpheniramine; Dihydrocodeine; Phenylephrine
  • Chlorpheniramine; Hydrocodone; Phenylephrine
  • Chlorpheniramine; Phenylephrine
  • Chlorthalidone
  • Chlorthalidone; Clonidine
  • Clomipramine
  • Clonidine
  • Cocaine
  • Codeine; Phenylephrine; Promethazine
  • Colchicine
  • Colchicine; Probenecid
  • Dapagliflozin
  • Dapagliflozin; Metformin
  • Dapagliflozin; Saxagliptin
  • Desflurane
  • Desipramine
  • Desvenlafaxine
  • Dextroamphetamine
  • Dextromethorphan; Diphenhydramine; Phenylephrine
  • Dextromethorphan; Guaifenesin; Phenylephrine
  • Digitoxin
  • Digoxin
  • Dihydroergotamine
  • Dipeptidyl Peptidase-4 Inhibitors
  • Diphenhydramine; Hydrocodone; Phenylephrine
  • Diphenhydramine; Phenylephrine
  • Dopamine
  • Dorzolamide; Timolol
  • Doxazosin
  • Doxepin
  • Dronabinol
  • Droxidopa
  • Dulaglutide
  • Duloxetine
  • Dyphylline
  • Dyphylline; Guaifenesin
  • Empagliflozin
  • Empagliflozin; Linagliptin
  • Empagliflozin; Linagliptin; Metformin
  • Empagliflozin; Metformin
  • Enalapril; Hydrochlorothiazide, HCTZ
  • Enflurane
  • Ephedrine
  • Epoprostenol
  • Eprosartan; Hydrochlorothiazide, HCTZ
  • Ergoloid Mesylates
  • Ergonovine
  • Ergot alkaloids
  • Ergotamine
  • Ertugliflozin
  • Ertugliflozin; Metformin
  • Ertugliflozin; Sitagliptin
  • Esketamine
  • Esmolol
  • Exenatide
  • Fluticasone; Salmeterol
  • Fluticasone; Umeclidinium; Vilanterol
  • Fluticasone; Vilanterol
  • Formoterol
  • Formoterol; Mometasone
  • Fosinopril; Hydrochlorothiazide, HCTZ
  • Glimepiride; Pioglitazone
  • Glimepiride; Rosiglitazone
  • Glycopyrrolate; Formoterol
  • Green Tea
  • Guaifenesin; Phenylephrine
  • Guanabenz
  • Halogenated Anesthetics
  • Halothane
  • Hydralazine; Hydrochlorothiazide, HCTZ
  • Hydrochlorothiazide, HCTZ
  • Hydrochlorothiazide, HCTZ; Irbesartan
  • Hydrochlorothiazide, HCTZ; Lisinopril
  • Hydrochlorothiazide, HCTZ; Losartan
  • Hydrochlorothiazide, HCTZ; Methyldopa
  • Hydrochlorothiazide, HCTZ; Metoprolol
  • Hydrochlorothiazide, HCTZ; Moexipril
  • Hydrochlorothiazide, HCTZ; Olmesartan
  • Hydrochlorothiazide, HCTZ; Propranolol
  • Hydrochlorothiazide, HCTZ; Quinapril
  • Hydrochlorothiazide, HCTZ; Spironolactone
  • Hydrochlorothiazide, HCTZ; Telmisartan
  • Hydrochlorothiazide, HCTZ; Triamterene
  • Hydrochlorothiazide, HCTZ; Valsartan
  • Hydrocodone; Phenylephrine
  • Iloprost
  • Imipramine
  • Incretin Mimetics
  • Indacaterol
  • Indacaterol; Glycopyrrolate
  • Indapamide
  • Insulin Degludec; Liraglutide
  • Insulin Glargine; Lixisenatide
  • Insulins
  • Iobenguane I 131
  • Iohexol
  • Iopamidol
  • Iopromide
  • Ioversol
  • Isocarboxazid
  • Isoflurane
  • Isosulfan Blue
  • Labetalol
  • Levalbuterol
  • Levobetaxolol
  • Levobunolol
  • Levomilnacipran
  • Levothyroxine
  • Levothyroxine; Liothyronine (Porcine)
  • Levothyroxine; Liothyronine (Synthetic)
  • Linezolid
  • Liothyronine
  • Liraglutide
  • Lisdexamfetamine
  • Lixisenatide
  • Lorcaserin
  • Macitentan
  • Maprotiline
  • Mecamylamine
  • Meglitinides
  • Metaproterenol
  • Metformin; Pioglitazone
  • Metformin; Rosiglitazone
  • Methamphetamine
  • Methyclothiazide
  • Methyldopa
  • Methylergonovine
  • Methysergide
  • Metolazone
  • Metoprolol
  • Midodrine
  • Miglitol
  • Milnacipran
  • Mirtazapine
  • Monoamine oxidase inhibitors
  • Nabilone
  • Nadolol
  • Nebivolol
  • Nebivolol; Valsartan
  • Nitrates
  • Non-Ionic Contrast Media
  • Norepinephrine
  • Nortriptyline
  • Orlistat
  • Ozanimod
  • Penbutolol
  • Pergolide
  • Perphenazine; Amitriptyline
  • Phendimetrazine
  • Phenelzine
  • Phenoxybenzamine
  • Phentolamine
  • Phenylephrine
  • Phenylephrine; Promethazine
  • Pindolol
  • Pioglitazone
  • Pirbuterol
  • Pramlintide
  • Prazosin
  • Procarbazine
  • Propranolol
  • Protriptyline
  • Rasagiline
  • Reserpine
  • Riociguat
  • Rosiglitazone
  • Safinamide
  • Salmeterol
  • Selective serotonin reuptake inhibitors
  • Selegiline
  • Selexipag
  • Semaglutide
  • Serotonin norepinephrine reuptake inhibitors
  • Sevoflurane
  • SGLT2 Inhibitors
  • Sibutramine
  • Sodium Oxybate
  • Solriamfetol
  • Sotalol
  • St. John’s Wort, Hypericum perforatum
  • Sulfonylureas
  • Tedizolid
  • Terazosin
  • Terbutaline
  • Theophylline, Aminophylline
  • Thiazide diuretics
  • Thiazolidinediones
  • Thyroid hormones
  • Timolol
  • Tranylcypromine
  • Treprostinil
  • Tricyclic antidepressants
  • Trimipramine
  • Umeclidinium; Vilanterol
  • Vasodilators
  • Vasopressors
  • Venlafaxine
  • Vilazodone
  • Vortioxetine
  • Yohimbine
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