Measles Mumps Rubella Vaccine

Measles Mumps Rubella Vaccines Brand Name– M M R II

What is Measles Mumps Rubella Vaccine

‘MMR’ is a combination subcutaneous injection consisting of three live virus vaccinations intended to confer immunity against measles (rubeola), mumps, and rubella (German measles).

The MMR vaccination is indicated in all children 12—15 months of age or older; for susceptible, nonpregnant adolescent and adult women; for postpartum, nonimmunized women; and for certain other adults (see Dosage).

The MMR consists of the measles vaccine virus live (derived from Enders’ attenuated Edmonston strain and propagated in chick embryo cell culture), the mumps virus vaccine live (Jeryl Lynn strain propagated in chick embryo cell culture), and the rubella virus vaccine live (Wistar RA 27/3 strain propagated in human diploid [WI-38] lung fibroblasts).

Indications

  • measles prophylaxis
  • mumps prophylaxis
  • rubella prophylaxis

For measles prophylaxis, mumps prophylaxis, and rubella prophylaxis

NOTE: Vaccination with MMR is recommended for persons susceptible to measles, mumps, and rubella. Adults born before 1957 are considered immune.

Side Effects

  1. acute disseminated encephalomyelitis
  2. anaphylactic shock
  3. anaphylactoid reactions
  4. angioedema
  5. arthralgia
  6. aseptic meningitis
  7. ataxia
  8. bronchospasm
  9. conjunctivitis
  10. diarrhea
  11. encephalopathy
  12. erythema
  13. erythema multiforme
  14. fever
  15. Guillain-Barre syndrome
  16. headache
  17. injection site reaction
  18. irritability
  19. maculopapular rash
  20. malaise
  21. musculoskeletal pain
  22. myalgia
  23. nausea
  24. neuritis
  25. optic neuritis
  26. panniculitis
  27. paresthesias
  28. pruritus
  29. purpura
  30. seizures
  31. Stevens-Johnson syndrome
  32. syncope
  33. thrombocytopenia
  34. urticaria
  35. vasculitis
  36. vomiting

Monitoring Parameters

  • laboratory monitoring not necessary

Contraindications

  • acquired immunodeficiency syndrome (AIDS)
  • agammaglobulinemia
  • albumin hypersensitivity
  • bone marrow suppression
  • breast-feeding
  • chemotherapy
  • egg hypersensitivity
  • fever
  • gelatin hypersensitivity
  • human immunodeficiency virus (HIV) infection
  • hypogammaglobulinemia
  • IgA deficiency
  • immune thrombocytopenic purpura (ITP)
  • immunosuppression
  • infants
  • infection
  • intramuscular administration
  • intravenous administration
  • leukemia
  • lymphoma
  • neomycin hypersensitivity
  • neonates
  • neoplastic disease
  • pregnancy
  • radiation therapy
  • respiratory infection
  • seizure disorder
  • severe combined immunodeficiency (SCID)
  • thrombocytopenia
  • tuberculosis

Interactions

  • Abatacept
  • Adalimumab
  • Aldesleukin, IL-2
  • Alefacept
  • Alemtuzumab
  • Alkylating agents
  • Alpha interferons
  • Altretamine
  • Anakinra
  • Antimetabolites
  • Antithymocyte Globulin
  • Antitumor antibiotics
  • Axicabtagene Ciloleucel
  • Azathioprine
  • Baricitinib
  • Basiliximab
  • Belatacept
  • Belimumab
  • Bexarotene
  • Blinatumomab
  • Brodalumab
  • Busulfan
  • Canakinumab
  • Carmustine, BCNU
  • Certolizumab pegol
  • Chlorambucil
  • Cisplatin
  • Clofarabine
  • Cortisone
  • Cyclophosphamide
  • Cyclosporine
  • Cytarabine, ARA-C
  • Cytomegalovirus Immune Globulin, CMV-IGIV
  • Dacarbazine, DTIC
  • Daclizumab
  • Deflazacort
  • Dexamethasone
  • Docetaxel
  • Dupilumab
  • Efalizumab
  • Emapalumab
  • Estramustine
  • Etanercept
  • Everolimus
  • Fingolimod
  • Floxuridine
  • Fludrocortisone
  • Fluorouracil, 5-FU
  • Folate analogs
  • Golimumab
  • Guselkumab
  • Hepatitis B Immune Globulin, HBIG
  • Hyaluronidase, Recombinant; Immune Globulin
  • Hydrocortisone
  • Ifosfamide
  • Imatinib
  • Immune Globulin IV, IVIG, IGIV
  • Inebilizumab
  • Infliximab
  • Interferon Gamma-1b
  • Ixabepilone
  • Ixekizumab
  • Leflunomide
  • Lenalidomide
  • Lomustine, CCNU
  • Mechlorethamine, Nitrogen Mustard
  • Melphalan
  • Methylprednisolone
  • Mitoxantrone
  • Muromonab-CD3
  • Mycophenolate
  • Natalizumab
  • Nelarabine
  • Nilotinib
  • Obinutuzumab
  • Ocrelizumab
  • Ofatumumab
  • Ozanimod
  • Paclitaxel
  • Prednisolone
  • Prednisone
  • Procarbazine
  • Purine analogs
  • Rabies Immune Globulin, human RIG
  • Rh0 [D] Immune Globulin
  • Rilonacept
  • Risankizumab
  • Rituximab
  • Rituximab; Hyaluronidase
  • Sarilumab
  • Secukinumab
  • Siltuximab
  • Siponimod
  • Sirolimus
  • Streptozocin
  • Tacrolimus
  • Temozolomide
  • Temsirolimus
  • Teriflunomide
  • Tetanus Immune Globulin, Human, TIG
  • Thiotepa
  • Tildrakizumab
  • Tisagenlecleucel
  • Tocilizumab
  • Tofacitinib
  • Tositumomab
  • Triamcinolone
  • Tuberculin Purified Protein Derivative, PPD
  • Ustekinumab
  • Varicella-Zoster Immune Globulin
  • Vedolizumab
  • Venetoclax
  • Vincristine
  • Vincristine Liposomal
  • Vinorelbine