Measles Mumps Rubella Vaccines Brand Name– M M R II
What is Measles Mumps Rubella Vaccine
‘MMR’ is a combination subcutaneous injection consisting of three live virus vaccinations intended to confer immunity against measles (rubeola), mumps, and rubella (German measles).
The MMR vaccination is indicated in all children 12—15 months of age or older; for susceptible, nonpregnant adolescent and adult women; for postpartum, nonimmunized women; and for certain other adults (see Dosage).
The MMR consists of the measles vaccine virus live (derived from Enders’ attenuated Edmonston strain and propagated in chick embryo cell culture), the mumps virus vaccine live (Jeryl Lynn strain propagated in chick embryo cell culture), and the rubella virus vaccine live (Wistar RA 27/3 strain propagated in human diploid [WI-38] lung fibroblasts).
Indications
- measles prophylaxis
- mumps prophylaxis
- rubella prophylaxis
For measles prophylaxis, mumps prophylaxis, and rubella prophylaxis
NOTE: Vaccination with MMR is recommended for persons susceptible to measles, mumps, and rubella. Adults born before 1957 are considered immune.
Side Effects
- acute disseminated encephalomyelitis
- anaphylactic shock
- anaphylactoid reactions
- angioedema
- arthralgia
- aseptic meningitis
- ataxia
- bronchospasm
- conjunctivitis
- diarrhea
- encephalopathy
- erythema
- erythema multiforme
- fever
- Guillain-Barre syndrome
- headache
- injection site reaction
- irritability
- maculopapular rash
- malaise
- musculoskeletal pain
- myalgia
- nausea
- neuritis
- optic neuritis
- panniculitis
- paresthesias
- pruritus
- purpura
- seizures
- Stevens-Johnson syndrome
- syncope
- thrombocytopenia
- urticaria
- vasculitis
- vomiting
Monitoring Parameters
- laboratory monitoring not necessary
Contraindications
- acquired immunodeficiency syndrome (AIDS)
- agammaglobulinemia
- albumin hypersensitivity
- bone marrow suppression
- breast-feeding
- chemotherapy
- egg hypersensitivity
- fever
- gelatin hypersensitivity
- human immunodeficiency virus (HIV) infection
- hypogammaglobulinemia
- IgA deficiency
- immune thrombocytopenic purpura (ITP)
- immunosuppression
- infants
- infection
- intramuscular administration
- intravenous administration
- leukemia
- lymphoma
- neomycin hypersensitivity
- neonates
- neoplastic disease
- pregnancy
- radiation therapy
- respiratory infection
- seizure disorder
- severe combined immunodeficiency (SCID)
- thrombocytopenia
- tuberculosis
Interactions
- Abatacept
- Adalimumab
- Aldesleukin, IL-2
- Alefacept
- Alemtuzumab
- Alkylating agents
- Alpha interferons
- Altretamine
- Anakinra
- Antimetabolites
- Antithymocyte Globulin
- Antitumor antibiotics
- Axicabtagene Ciloleucel
- Azathioprine
- Baricitinib
- Basiliximab
- Belatacept
- Belimumab
- Bexarotene
- Blinatumomab
- Brodalumab
- Busulfan
- Canakinumab
- Carmustine, BCNU
- Certolizumab pegol
- Chlorambucil
- Cisplatin
- Clofarabine
- Cortisone
- Cyclophosphamide
- Cyclosporine
- Cytarabine, ARA-C
- Cytomegalovirus Immune Globulin, CMV-IGIV
- Dacarbazine, DTIC
- Daclizumab
- Deflazacort
- Dexamethasone
- Docetaxel
- Dupilumab
- Efalizumab
- Emapalumab
- Estramustine
- Etanercept
- Everolimus
- Fingolimod
- Floxuridine
- Fludrocortisone
- Fluorouracil, 5-FU
- Folate analogs
- Golimumab
- Guselkumab
- Hepatitis B Immune Globulin, HBIG
- Hyaluronidase, Recombinant; Immune Globulin
- Hydrocortisone
- Ifosfamide
- Imatinib
- Immune Globulin IV, IVIG, IGIV
- Inebilizumab
- Infliximab
- Interferon Gamma-1b
- Ixabepilone
- Ixekizumab
- Leflunomide
- Lenalidomide
- Lomustine, CCNU
- Mechlorethamine, Nitrogen Mustard
- Melphalan
- Methylprednisolone
- Mitoxantrone
- Muromonab-CD3
- Mycophenolate
- Natalizumab
- Nelarabine
- Nilotinib
- Obinutuzumab
- Ocrelizumab
- Ofatumumab
- Ozanimod
- Paclitaxel
- Prednisolone
- Prednisone
- Procarbazine
- Purine analogs
- Rabies Immune Globulin, human RIG
- Rh0 [D] Immune Globulin
- Rilonacept
- Risankizumab
- Rituximab
- Rituximab; Hyaluronidase
- Sarilumab
- Secukinumab
- Siltuximab
- Siponimod
- Sirolimus
- Streptozocin
- Tacrolimus
- Temozolomide
- Temsirolimus
- Teriflunomide
- Tetanus Immune Globulin, Human, TIG
- Thiotepa
- Tildrakizumab
- Tisagenlecleucel
- Tocilizumab
- Tofacitinib
- Tositumomab
- Triamcinolone
- Tuberculin Purified Protein Derivative, PPD
- Ustekinumab
- Varicella-Zoster Immune Globulin
- Vedolizumab
- Venetoclax
- Vincristine
- Vincristine Liposomal
- Vinorelbine
