How do PGs protect the gastric mucosa

How do PGs protect the gastric mucosa?

  • PGE1 and PGE2 effects on gastric mucosa:
    • • Induce protective superficial mucous barrier.
    • • Induce bicarbonate output.
    • • Increase mucosal blood flow in the superficial gastric cell layer.
    • • Inhibit gastric acid synthesis.
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