Gallium Ga 68 Dotatate

Gallium Ga 68 Dotatate Brand Name– NETSPOT

What is Gallium Ga 68 Dotatate

Gallium Ga 68 dotatate is a radioactive diagnostic agent for use with positron emission tomography (PET) for localization of somatostatin receptor positive neuroendocrine tumors (NETs) in adults and pediatric patients.

NETs are rare benign or malignant tumors that develop in the hormone-producing cells of the body’s neuroendocrine system, which are found in the stomach, intestines, pancreas, lungs, and other locations. NETs have receptors for somatostatin, a hormone that regulates the endocrine system.

The uptake of gallium Ga 68 dotatate reflects the level of somatostatin receptor density in NETs. This uptake can also be seen in a variety of other tumor types or other pathologic conditions, or might occur as a normal variant.

The uptake of gallium Ga 68 dotatate may need to be confirmed by histopathology or other assessments.

Gallium Ga 68 dotatate was FDA-approved in June 2016.

Indications

  • positron emission tomography (PET) imaging

For use with positron emission tomography (PET) imaging for localization of somatostatin receptor positive neuroendocrine tumors (NETs)

NOTE: This drug is a radiopharmaceutical and should only be administered by individuals specifically trained in the handling of radioactive material.

NOTE: Dosage measured in megabecquerels (MBq) and millicuries (mCi).

Side Effects

  1. injection site reaction
  2. nausea
  3. vomiting

Monitoring Parameters

  • laboratory monitoring not necessary

Contraindications

  • accidental exposure
  • breast-feeding
  • inflammation
  • pregnancy
  • radiation exposure
  • thyroid disease

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