Ethanolamine Brand Name– Ethamolin
What is Ethanolamine
Ethanolamine oleate is an intravenous sclerosing agent. It is indicated to prevent rebleeding in varices that have bled.
Ethanolamine has not been shown to be effective for prophylaxis. Ethanolamine causes irritation of the intimal endothelium of the vein and produces an inflammatory response.
This drug was approved by the FDA in 1988.
Indications
- esophageal varices
For the treatment of patients with esophageal varices that have recently bled, to prevent rebleeding
NOTE: Ethanolamine is not indicated for the treatment of esophageal varices that have not bled, as supportive data that ethanolamine will decrease the likelihood of bleeding in this population are lacking. Sclerotherapy with ethanolamine has no effect on portal hypertension, the cause of esophageal varices. Recanalization and collateralization may occur, requiring further treatment.
Side Effects
- anaphylactic shock
- anaphylactoid reactions
- disseminated intravascular coagulation (DIC)
- esophageal stricture
- esophageal ulceration
- esophagitis
- fever
- infection
- pleural effusion
- pneumonitis
- pulmonary edema
- renal failure (unspecified)
- tissue necrosis
Monitoring Parameters
- LFTs
Contraindications
- breast-feeding
- cardiac disease
- children
- geriatric
- hepatic disease
- infants
- neonates
- pregnancy
- requires an experienced clinician
- respiratory insufficiency
Interactions
There are no drug interactions associated with Ethanolamine products.
