Are there any characteristics of Glucocorticoids preparations that are important to consider when determining which to use for injection therapy

Are there any characteristics of Glucocorticoids preparations that are important to consider when determining which to use for injection therapy?

Solubility of the GC preparation is an important factor when considering injection therapy. Reducing the solubility of a compound increases the duration of the local effect because diffusion of the medication will be slower. Thus, less soluble (i.e., fluorinated) preparations have greater potency but are also more likely to result in adverse consequences.

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