Anthralin

Anthralin Brand Names

Dritho-Creme HP | Dritho-Scalp | Micanol | Psoriatec | ZITHRANOL | ZITHRANOL-RR

What is Anthralin

Anthralin (also known as dithranol) is a synthetic topical antipsoriatic agent and a derivative of anthracene.

It is used for quiescent or chronic psoriasis. Anthralin also may be used for alopecia, although it is not FDA-approved for this indication.

Do not apply to face, genitalia, eyes, open sores, or mucous membranes because painful irritation can occur.

Protective dressings to shield unaffected skin are recommended.

This agent can stain fabric, skin, or hair with a yellow-brown color; stains can be permanent.

Anthralin was initially marketed for use before 1962, which is when Congress passed the amended Federal Food, Drug, and Cosmetic Act requiring that the FDA establish both safety and efficacy for all subsequently approved drugs.

Anthralin products are unapproved marketed drugs that have not been formally evaluated by the FDA.

Indications

  • alopecia
  • psoriasis

For the treatment of stable plaque psoriasis

Side Effects

  1. hair discoloration
  2. nail discoloration
  3. photosensitivity
  4. skin discoloration
  5. skin irritation

Monitoring Parameters

  • laboratory monitoring not necessary

Contraindications

  • breast-feeding
  • children
  • infants
  • neonates
  • ocular exposure
  • pregnancy
  • sunlight (UV) exposure

Interactions

There are no drug interactions associated with Anthralin products.

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