How do cyst fluid carcinoembryonic antigen and amylase help differentiate among the common pancreatic cystic lesions? Levels of CEA and Amylase in Pancreatic Cystic Lesions Type of Cyst CEA Amylase Pseudocyst ↓ (< 192 ng/mL) ↑ (> 250 U/L) Serous cystadenoma ↓ ↓ Mucinous cystic neoplasm ↑ ↓ Intraductal papillary mucinous neoplasm ↑ ↑ CEA, Carcinoembryonic antigen.
Accuracy of EUS imaging and cytologic examination in diagnosing pancreatic cystic lesions EUS imaging differentiates mucinous from nonmucinous cysts with 50% accuracy. Sensitivity of EUS-FNA cytologic examination for distinguishing mucinous from nonmucinous cysts is less than 50%.
What is the role of EUS in suspected choledocholithiasis? This depends on the probability of choledocholithiasis being present based on clinical and imaging findings. In patients with high probability of choledocholithiasis (total bilirubin > 4 mg/dL or common bile duct (CBD) stone seen on radiologic imaging, or both dilated CBD with bilirubin 1.8-4 mg/dL), ERCP …
How does EUS compare with endoscopic retrograde cholangiopancreatography (ERCP), magnetic resonance cholangiopancreatography (MRCP), and abdominal ultrasound for detection of choledocholithiasis? ERCP, MRCP, and EUS have comparable sensitivity and specificity for choledocholithiasis (85%-95%, 92%-98%, respectively). Although the overall accuracy of EUS is comparable to MRCP for choledocholithiasis, EUS is superior for stones smaller than 5 mm …
Diagnostic yield of EUS-FNA in subepithelial lesions versus other diagnostic techniques EUS-FNA has modest diagnostic yield in subepithelial lesions of approximately 60%. Endoscopic mucosal resection has high diagnostic yield (87%) with standard forcep bite-on-bite biopsies having the lowest yield (38%). Performing five FNA passes and having an on-site cytologist present may increase yield of EUS-FNA. …
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What are common subepithelial lesions and their EUS characteristics Common Subepithelial Lesions and EUS Characteristics Subepithelial Lesion EUS Characteristic Gastrointestinal stromal tumor Hypoechoic, second or fourth layer Lipoma Hyperechoic, third layer Carcinoid Mildly hypoechoic, second or third layer Cyst Anechoic, second or third layer Pancreatic rest Hypoechoic or heterogeneous, second, third, or fourth layer Granular …
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What is the role of EUS in pancreatic neuroendocrine tumors (PNETs)? EUS is an integral part of both detecting and diagnosing PNETs with 77% to 94% sensitivity for detecting them. When abdominal CT scan is negative for PNET, EUS is more than 70% sensitive for detecting it. EUS is superior to CT scan for small …