What is Pertuzumab Trastuzumab Hyaluronidase Pertuzumab trastuzumab hyaluronidase is a combination product for subcutaneous use. Both pertuzumab and trastuzumab are monoclonal antibodies and human epidermal growth factor receptor 2 (HER2)/neu-receptor antagonists; these drugs bind to different sites on HER2. Hyaluronidase-zzxf is an endoglycosidase used to increase the dispersion and absorption of coadministered drugs when administered …
Pertuzumab Brand Name– PERJETA What is Pertuzumab Pertuzumab is a humanized recombinant monoclonal antibody that blocks ligand-dependent heterodimerization of human epidermal growth factor receptor-2 (HER2) and other epidermal growth factor receptors resulting in the inhibition of intracellular signaling pathways and eventually cell growth arrest and apoptosis. Pertuzumab also demonstrates antibody-dependent cell-mediated cytotoxicity. It was FDA-approved …
Perphenazine and Amitriptyline Brand Names- Etrafon | Etrafon-A | Triavil What is Perphenazine and Amitriptyline Perphenazine and amitriptyline is an oral combination product containing a phenothiazine antipsychotic (perphenazine) and a tricyclic antidepressant (amitriptyline). Perphenazine and amitriptyline is indicated in patients with schizophrenia and associated depressive symptoms. This combination is also used for combined depression with moderate to …
Perphenazine Brand Name– Trilafon What is Perphenazine Perphenazine is an oral antipsychotic agent. It is a piperazine phenothiazine and is structurally similar to trifluoperazine, prochlorperazine, and fluphenazine. The Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) study evaluated the effectiveness of selected atypical antipsychotics and perphenazine in schizophrenic patients. The primary outcome measure was discontinuation of …
Permethrin Brand Names Acticin | Elimite | Nix Lice Killing Creme Rinse What is Permethrin Permethrin is a synthetic pyrethroid used primarily as a topical scabicide and pediculicide. Permethrin is a synthetic mixture of cis- and trans- isomers of pyrethrin chemically altered have more light and heat stability versus the natural pyrethrins. Permethrin is a commonly used …
Perindopril and Amlodipine Brand Name– Prestalia What is Perindopril and Amlodipine Perindopril and Amlodipine are used together in an oral preparation to treat hypertension. Amlodipine is a dihydropyridine calcium channel blocker and is a potent peripheral vasodilator, similar to nifedipine and other members of the dihydropyridine class. Amlodipine has the longest half-life of the group, …
Perindopril Brand Name– Aceon What is Perindopril Perindopril is an oral angiotensin-converting enzyme (ACE) inhibitor which is used alone or in combination therapy for hypertension. It is a prodrug that is hydrolyzed to perindoprilat. Perindopril is an intermediate-acting ACE inhibitor, allowing for once or twice daily dosing. In general, ACE inhibitors appear to have a …