What is Tafluprost Tafluprost is a prostaglandin analog with a high affinity for the fluoroprostaglandin (FP) receptor. It is indicated for reducing elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. In clinical studies, administration of tafluprost 0.0015% once daily to patients with open-angle glaucoma or ocular hypertension and a baseline IOP …
What is Tafenoquine Tafenoquine is an oral antimalarial indicated for malaria prophylaxis in adults and for the radical cure (prevention of relapse) of Plasmodium vivax malaria in patients aged 16 years and older who are receiving appropriate antimalarial therapy for acute P. vivax infection. Tafenoquine is not indicated for the acute treatment of P. vivax infection. Screening of all patients for …
What is Tafamidis Tafamidis, a selective transthyretin (TTR) stabilizer, is indicated for the treatment of the cardiomyopathy of wild type or hereditary transthyretin-mediated amyloidosis in adults to reduce cardiovascular mortality and cardiovascular-related hospitalization. A significant reduction in all-cause mortality and cardiovascular-related hospitalization occurred with tafamidis therapy (20 mg once daily and 80 mg once daily) …
What is Tadalafil Tadalafil is a selective phosphodiesterase type 5 (PDE5) inhibitor similar to sildenafil and vardenafil. It is administered orally for the treatment of pulmonary arterial hypertension (PAH), male erectile dysfunction (ED), benign prostatic hypertrophy (BPH), or the concurrent treatment of ED and BPH. Tadalafil does not inhibit prostaglandins as do some agents for …
What is Tacrolimus Tacrolimus is a calcineurin-inhibitor immunosuppressive agent that has been studied in patients receiving heart, kidney, liver, lung, pancreas, small bowel, or bone marrow transplants. Tacrolimus has been shown to be effective in graft rejection prophylaxis and in the management of acute and steroid- or cyclosporine-resistant transplant rejection, and it is considered an …
What is Tacrine Tacrine hydrochloride is a cholinesterase (ChE) inhibitor. It was the first drug approved for improving cognitive symptoms (i.e., memory, attention, reason, language, and the ability to perform simple tasks) associated with Alzheimer’s disease. A recent meta-analysis of 12 trials involving 1984 patients treated with tacrine for up to 1 year showed that …
What is Ruxolitinib Ruxolitinib is a kinase inhibitor that inhibits Janus Associated Kinases (JAKs), JAK1 and JAK2. It is indicated for the treatment of adults with intermediate- or high-risk myelofibrosis (e.g., primary myelofibrosis, post-polycythemia vera myelofibrosis, and post-essential thrombocythemia myelofibrosis), adults with polycythemia vera who have had an inadequate response to or are intolerant of …