What is Tolterodine Tolterodine is a antimuscarinic anticholinergic agent administered orally for the treatment of patients with overactive bladder. Tolterodine helps to reduce urinary frequency and urgency, and helps to reduce urge-related incontinence. Tolterodine has been studied extensively in the elderly, and may be preferred in the geriatric population over other antimuscarinic drugs for overactive …
What is Tolnaftate Tolnaftate is a synthetic topical thiocarbamate antifungal agent. It is used primarily for the treatment of mild to moderate tinea pedis (athlete’s foot), tinea cruris (jock itch), tinea corporis (ringworm), tinea manuum, and tinea versicolor in immunocompetent patients. The causative dermatophytes (fungi that require keratin to grow) are Trichophyton rubrum, T. mentagrophytes, T. tonsurans, Microsporum canis, M. …
What is Tolmetin Tolmetin is a nonsteroidal anti-inflammatory drug (NSAID) of the acetic acid chemical class. Tolmetin possesses analgesic and antipyretic properties. Its anti-inflammatory action equates to aspirin, although tolmetin generally is better tolerated. Tolmetin may have additive effects when used with corticosteroids or other arthritis therapies. Initial beneficial effects of tolmetin for arthritis may …
What is Tolcapone Tolcapone is an oral peripherally and centrally-acting catechol-O-methyltransferase (COMT) inhibitor used as an adjunct to levodopa/carbidopa therapy in the treatment of Parkinson’s disease. Clinically, COMT inhibitors improve levodopa availability in the CNS, thereby prolonging the motor response to levodopa treatment. Tolcapone usually allows the patient’s dosage of levodopa to be lowered, and …
What is Tolbutamide Tolbutamide is a ‘first-generation’ oral sulfonylurea antidiabetic agent used as an adjunct to diet to control blood glucose in patients with type 2 diabetes mellitus (DM). Tolbutamide is the shortest-acting and least potent sulfonylurea; its duration of action is 6 to 12 hours. Since it is extensively metabolized to inactive metabolites, tolbutamide …
What is Tolazamide Tolazamide is a ‘first-generation’ oral sulfonylurea antidiabetic agent with an intermediate duration of action. It is used as an adjunct to diet to lower blood glucose in patients with type 2 diabetes mellitus (DM). Although the mechanism for sulfonylureas is similar, there are quantitative differences in their individual pharmacokinetic properties. Tolazamide tends …
What is Tofacitinib Tofacitinib is an oral Janus kinase (JAK) inhibitor, and is considered a targeted synthetic disease-modifying antirheumatic drug (tsDMARD). Janus kinases are intracellular enzymes that transmit signals arising from cytokine interactions on the cellular membrane to influence cellular processes of immune cell function. Tofacitinib has been shown useful for a variety of inflammatory …