What is Trifluridine Trifluridine (also known as trifluorothymidine) is an ophthalmic antiviral preparation indicated for primary keratoconjunctivitis and recurrent epithelial keratitis due to herpes simplex virus (HSV) types 1 and 2. Trifluridine is the treatment of choice for this indication and therapy is associated with a cure rate greater than 90%. HSV infections resistant to …
What is Trifluoperazine Trifluoperazine is a piperazine phenothiazine that is structurally similar to perphenazine, prochlorperazine, and fluphenazine. It is used to treat psychotic disorders and schizophrenia. A 5 mg trifluoperazine dose would be equivalent to 100 mg of chlorpromazine, the prototype antipsychotic. Trifluoperazine was approved by the FDA in 1958. All dosage forms of the …
What is Trifarotene Trifarotene is a retinoic acid receptor (RAR) agonist with specific activity at the gamma subtype of RAR. The drug is approved for the topical treatment of acne vulgaris in patients 9 years of age and older. Patients treated with trifarotene may experience local cutaneous adverse reactions, which are typically most severe within …
What is Trientine Trientine is an oral chelating agent that is used for the treatment of Wilson’s disease (hepatolenticular degeneration). Trientine is a copper chelator, but trientine is only indicated for use in patients who have intolerance to penicillamine, which is another copper chelator. Of 41 patients who got trientine because of d-penicillamine intolerance, 34 …
What is Triclabendazole Triclabendazole is an oral anthelmintic indicated for the treatment of fascioliasis in patients 6 years and older. It is given as a 2-dose regimen. QT prolongation was noted in animal studies. Gastrointestinal adverse reactions are common, but may also be secondary to the infection and may be more frequent or severe in …
What is Trichloroacetic Acid Trichloroacetic acid is a topical cauterizing agent recommended by the CDC for the treatment of condylomata acuminata, including warts found in the external genital/perianal areas. It has also been used as a chemical peel in the treatment of actinic keratoses and other signs of photoaging, including melasma and lentigines. Trichloroacetic acid …
What is Triazolam Triazolam is an oral benzodiazepine used as a hypnotic agent in the short-term management of insomnia. Compared to chlordiazepoxide, diazepam, and flurazepam, triazolam has a relatively shorter half-life and does not generate active metabolites. However, triazolam has been associated with numerous reports of retrograde amnesia. Doses should be reduced when used in …