What is Triprolidine Triprolidine is a first generation oral sedating antihistamine (H1-blocker) belonging to the alkylamine class. It is used for the treatment of allergic and vasomotor rhinitis, allergic conjunctivitis, and uncomplicated skin manifestations of angioedema and urticaria. Triprolidine was approved by the FDA in 1958. Indications & Dosage allergic conjunctivitis allergic rhinitis rhinorrhea sneezing …
What is Trimipramine Trimipramine is an oral tertiary amine tricyclic antidepressant (TCA). This drug is considered one of the most sedating TCAs. Trimipramine is FDA-approved to treat major depression in adult patients. The drug is not FDA-approved for use for treating depression in pediatric patients; suggestions for adolescent dosing are provided in manufacturer labels. Trimipramine …
What is Trimetrexate NOTE: This drug is discontinued in the US. Trimetrexate is a parenteral, non-classical folate antagonist. It is structurally similar to methotrexate and trimethoprim. Trimetrexate was approved as an orphan drug for the treatment of Pneumocystis pneumonia (PCP) in patients with AIDS. Other orphan drug designations include the treatment of metastatic colorectal carcinoma, head and …
What is Trimethoprim Trimethoprim is a synthetic antiinfective agent. It has activity against both gram-positive and gram-negative bacteria. It is commonly used systemically for the treatment and prophylaxis of uncomplicated urinary tract infections, for traveler’s diarrhea, and, when combined with either sulfamethoxazole or dapsone, for prophylaxis and treatment of Pneumocystis infections. Trimethoprim was originally available in combination …
What is Trimethobenzamide Trimethobenzamide is an oral, rectal, and parenteral antiemetic agent used to control nausea and vomiting. Structurally, the drug is a substituted benzamide with actions similar to metoclopramide, but trimethobenzamide is considered less potent. For example, trimethobenzamide is typically recommended only for control of nausea following chemotherapy of mild to moderate emetic potential. …
What is Trihexyphenidyl Trihexyphenidyl is an oral synthetic, tertiary antimuscarinic. Its anticholinergic actions are similar to those of atropine. Because it is a tertiary compound, it will penetrate the CNS. The drug is indicated as an adjunct in the treatment of all forms of parkinsonism (postencephalitic, arteriosclerotic, and idiopathic). It is often useful as adjuvant …
What is Trifluridine and Tipiracil combination medicine Trifluridine and tipiracil is a combination product that is FDA approved for the treatment of metastatic colorectal cancer and metastatic gastric or gastroesophageal junction cancer after progression on several previous lines of therapy. Trifluridine was initially developed in the 1960s but was abandoned due to a lack of …