Vorinostat Brand Name Zolinza What is Vorinostat Vorinostat is a histone deacetylase (HDAC) inhibitor. It is indicated for the treatment of cutaneous manifestations in patients with cutaneous T-cell lymphoma who have progressive, persistent or recurrent disease on or following 2 systemic therapies. Pulmonary embolism (PE) and deep vein thrombosis (DVT) have been reported with vorinostat …
Voriconazole Brand Name VFEND What is Voriconazole Voriconazole is an azole antifungal agent derived from the structure of fluconazole but was designed to enhance the potency and spectrum of activity of fluconazole. Voriconazole has been studied in a variety of fungal infections, including Aspergillosis, fluconazole-susceptible and -resistant Candida infections, and Cryptococcus neoformans. Unlike fluconazole, voriconazole exhibits activity against …
Voretigene Neparvovec Brand Name LUXTURNA What is Voretigene Neparvovec Voretigene neparvovec is an adeno-associated virus vector-based gene therapy indicated for the treatment of children and adults with biallelic RPE65 mutation-associated retinal dystrophy, an inherited form of vision loss. Biallelic RPE65 mutation-associated retinal dystrophy affects approximately 1,000 to 2,000 patients in the U.S. Mutations in the …
Vorapaxar Brand Name Zontivity What is Vorapaxar Vorapaxar is a competitive and selective antagonist of protease-activated receptor-1 (PAR-1), the major thrombin receptor on human platelets. It is approved for reduction in risk of myocardial infarction, stroke, cardiovascular death, and need for coronary revascularization in patients with a previous myocardial infarction or peripheral arterial disease (PAD). …
von Willebrand Factor Brand Name VONVENDI What is von Willebrand Factor von Willebrand factor is recombinant von Willebrand factor indicated for on-demand treatment, control of bleeding episodes, and perioperative management of bleeding in adults with von Willebrand disease. During clinical trials, all bleeding episodes (n = 193) treated with von Willebrand factor alone or von …
Vitamin A Brand Names A Mulsin Aquasol A Dofsol-A What is Vitamin A Vitamin A is a fat-soluble vitamin that is available from both plant and animal sources. Animal sources of vitamin A are referred to as retinoids, while carotenoids are the term applied to vitamin A precursors, such as beta-carotene, derived from plants. Retinoids …
Vismodegib Brand Name – Erivedge What is Vismodegib Vismodegib is an oral hedgehog pathway inhibitor. It is indicated for the treatment of adults with metastatic basal cell carcinoma (BCC) or in patients with locally advanced BCC that has recurred following surgery. Vismodegib is also indicated for patients with locally advanced BCC who are not candidates …