Eteplirsen Brand Name– Exondys 51 What is Eteplirsen Eteplirsen is an antisense oligonucleotide specifically indicated for the treatment of patients with Duchenne muscular dystrophy (DMD) who have a confirmed mutation of the dystrophin gene that makes them more likely to respond to exon 51 skipping. Approximately 13% of the DMD population has this mutation. DMD …
Etelcalcetide Brand Name– Parsabiv What is Etelcalcetide Etelcalcetide is an intravenous, calcimimetic and calcium-sensing receptor (CaSR) agonist indicated for secondary hyperparathyroidism in adults with chronic kidney disease on hemodialysis. Etelcalcetide is administered 3 times weekly at the end of hemodialysis sessions. Etelcalcetide lowers serum calcium which may lead to serious, life-threatening hypocalcemia associated with seizures, …
Etanercept Brand Names- Enbrel | ERELZI What is Etanercept Etanercept is a subcutaneously administered tumor necrosis factor (TNF) blocker that is a soluble TNF receptor. Like other TNF blockers, etanercept is useful in a variety of inflammatory disorders. In adults with rheumatoid arthritis (RA) or psoriatic arthritis (PsA) the drug improves clinical signs and symptoms, inhibits …
Eszopiclone Brand Name– Lunesta What is Eszopiclone Eszopiclone is a non-benzodiazepine sedative-hypnotic and the first indicated for chronic treatment of insomnia. Although chemically unrelated to other hypnotics, such as the benzodiazepines or barbiturates, eszopiclone does share some pharmacological actions with these drugs. Unlike the benzodiazepines, it produces muscle relaxation and anticonvulsant effects only at doses …
Estropipate Brand Names- Ogen | Ortho-Est What is Estropipate Estropipate is a synthesized estrogen, also known as piperazine-stabilized estrone sulfate. On a weight basis, 1.2 mg of estropipate is equivalent to 1 mg of sodium estrone sulfate. Most of the commercially available estrogen products are synthesized. There is no evidence that ‘natural’ estrogens are more or …
What is Estrone NOTE: These products are discontinued in the U.S. Estrone is a naturally occurring steroidal estrogen that is one-third less active at the cellular level than estradiol, the principal premenopausal human estrogen. Estrone is obtained from pregnant equine urine or prepared synthetically. Most commercially available estrone products are synthesized. There is no evidence …
Estramustine Brand Name– Emcyt What is Estramustine Estramustine is an oral, nitrogen mustard antineoplastic agent that is used to treat prostate cancer. Estramustine is a combination of an estradiol molecule linked to nornitrogen mustard. The oral compound contains a phosphate group that facilitates higher water solubility and oral absorption. In patients with hormone-refractory prostate cancer, …