Oxaliplatin Brand Name– Eloxatin What is Oxaliplatin Oxaliplatin is an intravenous, non cell-cycle specific, platinum-based alkylating agent. Unlike cisplatin or carboplatin, it is not associated with significant renal or auditory toxicity. It contains a bulky carrier ligand (1,2-diaminocyclohexane [DACH] which is not present in either cisplatin or carboplatin, contributing to a lack of cross-resistance with …
What is Oxacillin Oxacillin is a semisynthetic antistaphylococcal penicillin. Like other antistaphylococcal penicillins, oxacillin is stable against penicillinase, making it active against penicillinase-producing S. aureus. As a result, its main use is for treating infections caused by this organism, including bacteremia, skin and soft-tissue infections, respiratory tract infections, bone and joint infections, and urinary tract infections. …
Ospemifene Brand Name– Osphena What is Ospemifene Ospemifene is an oral estrogen receptor agonist/antagonist (selective estrogen-receptor modulator, or SERM) that is used to treat women experiencing moderate to severe vaginal dryness and dyspareunia, symptoms of vulvar and vaginal atrophy due to menopause. Ospemifene is not a hormone and is an alternative to estrogen therapy in …
Osimertinib Brand Name– Tagrisso What is Osimertinib Osimertinib is indicated for the treatment of patients with metastatic epidermal growth factor receptor (EGFR) mutation-positive non-small cell lung cancer (NSCLC): either as first-line therapy in patients with exon 19 deletions or exon 21 (L858R) substitution mutations, or after progression on EGFR tyrosine kinase inhibitor (TKI) therapy in …
Osilodrostat Brand Name– ISTURISA What is Osilodrostat Osilodrostat in an oral cortisol synthesis inhibitor that works by inhibiting steroid 11-beta-hydroxylase (also known as CYP11B1), an enzyme responsible for the final step of cortisol biosynthesis in the adrenal gland. Osilodrostat is used to treat adult patients with Cushing’s disease who cannot be treated with surgery, or …
Oseltamivir Brand Name– Tamiflu What is Oseltamivir Oseltamivir is an oral neuraminidase inhibitor (NAI) indicated for the treatment and prevention of acute, uncomplicated seasonal influenza infections. Like other NAIs (zanamivir and peramivir), oseltamivir has activity against both influenza A and B viruses; whereas adamantanes (amantadine and rimantadine) are active against influenza A only. Clinical benefit …
Orphenadrine Brand Name– Banflex | Norflex What is Orphenadrine Orphenadrine is an oral and parenteral, centrally acting muscle relaxant. It is the o-methyl analog of the antihistamine diphenhydramine. Orphenadrine is used as adjunct therapy for acute, painful musculoskeletal conditions. It has also been used adjunctively in treating arteriosclerotic, idiopathic, or postencephalic parkinsonism. Orphenadrine was approved by the …