Which neuropathic pain syndromes are commonly seen in patients with cancer?
Lumbosacral plexopathy may be caused by lymphoma or colon cancer. Injury to the intercostobrachial nerve during radical mastectomy may result in pain or numbness distal to the axilla on the inner aspect of the arm. The neuropathy that develops from chemotherapy with cisplatin or vinca alkaloids is dose-related and usually affects the extremities; sensory as well as motor neuropathies can occur (e.g., peroneal palsy). Cancer patients appear predisposed to developing herpes zoster (shingles) that can progress to postherpetic neuralgia (PHN; pain that persists >6 weeks after complete resolution of the shingles lesions). Complex Regional Pain Syndromes Type I and II, postradiation plexopathy, radiculopathy, and neuroma formation are other neuropathic syndromes seen in cancer patients.