Ragwitek (Short Ragweed Pollen Allergen Extract)

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What is Ragwitek

Ragwitek is Short Ragweed Pollen Allergen Extract Tablet for Sublingual Use .

Short ragweed pollen allergen extract is a sublingual immunotherapy (SLIT) approved for the treatment of allergic rhinitis with or without conjunctivitis that is induced by short ragweed pollen in adults aged 18—65 years

Brand Name

Ragwitek

Indications

  1. Immunotherapy for the treatment of short ragweed pollen-induced allergic rhinitis, with or without conjunctivitis, confirmed by positive skin test or in vitro testing for pollen-specific IgE antibodies for short ragweed pollen approved for use in adults 18 through 65 years of age.
  2. allergic conjunctivitis
  3. allergic rhinitis
  4. Hypersensitivity to short ragweed pollen should be confirmed by positive skin test or in vitro testing for pollen-specific IgE antibodies before administering.
  5. Initiate treatment at least 12 weeks prior to the expected onset of each ragweed pollen season and continue throughout the season.
  6. Safety and efficacy data regarding starting treatment during the ragweed pollen season are not available. Safety data regarding restarting treatment after missing a dose are limited; during clinical trials, treatment interruptions for up to 7 days were allowed.

Side Effects

  1. Oral pruritus
  2. Paraesthesia oral
  3. Mouth edema
  4. Tongue pruritus
  5. Lip swelling
  6. Swollen tongue
  7. Lip pruritus
  8. Dry mouth
  9. Tongue edema
  10. Nausea
  11. Palatal edema
  12. Dysphagia
  13. Chest discomfort
  14. Itching in the ear
  15. Throat irritation
  16. Oropharyngeal pain
  17. Throat tightness
  18. anaphylactic shock
  19. anaphylactoid reactions
  20. angioedema
  21. chest pain (unspecified)
  22. dysphagia
  23. dysphonia
  24. edema
  25. esophagitis
  26. nausea
  27. paresthesias
  28. pruritus
  29. serious hypersensitivity reactions or anaphylaxis
  30. throat irritation
  31. xerostomia

Monitoring Parameters

  • laboratory monitoring not necessary

Contraindications

  • acute bronchospasm
  • angina
  • asthma
  • atopy
  • breast-feeding
  • cardiac arrhythmias
  • chronic lung disease (CLD)
  • chronic obstructive pulmonary disease (COPD)
  • dental work
  • emphysema
  • eosinophilic esophagitis
  • gelatin hypersensitivity
  • hypertension
  • inflammation
  • mannitol hypersensitivity
  • myocardial infarction
  • pregnancy
  • requires a specialized care setting
  • serious hypersensitivity reactions or anaphylaxis
  • status asthmaticus
  • sublingual allergen immunotherapy hypersensitivity

Interactions

There are no drug interactions associated with Short Ragweed Pollen Allergen Extract products.

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