Cloistered syndrome

Cloistered syndrome

Cloistered syndrome (LIS) is a rare medical disease affecting the neurological system.

Features of Cloistered syndrome

  • Sustained eye opening
  • quadriplegia or quadriparesis
  • anarthria
  • preserved cognitive functions
  • and a primary code of communication using vertical eye movements or blinking

Symptoms of Cloistered syndrome

Very Common Symptoms and Signs (80%-98%)

  • Abnormality of the eye 
  • Abnormality of the voice 
  • Abnormality of vision 
  • Anarthria 
  • Behavioral abnormality 
  • Cerebral palsy 
  • Diplopia 
  • Hypertonia 
  • Respiratory insufficiency 
  • Spasticity
  • Tetraparesis 
  • Tetraplegia 

Common Symptoms and Signs (30%-79%)

  • Excessive salivation 
  • Feeding difficulties 
  • Recurrent respiratory infections 

Occasional Symptoms and Signs (5%-29%)

Hearing impairment 


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