Which clinical syndromes are most commonly associated with elevated levels of Antiphospholipid Antibodies?
Clinical syndromes most commonly associated with aPL abs can be remembered by the mnemonic CLOT:
- C —Clot: recurrent arterial and/or venous thrombosis (clots).
- L —Livedo reticularis: lace-like rash over the extremities and trunk exaggerated by cold conditions.
- O —Obstetrical complications: recurrent fetal loss, placental ischemic conditions (preeclampsia, intrauterine growth restriction).
- T —Thrombocytopenia.