Which clinical syndromes are most commonly associated with elevated levels of Antiphospholipid Antibodies

Which clinical syndromes are most commonly associated with elevated levels of Antiphospholipid Antibodies?

Clinical syndromes most commonly associated with aPL abs can be remembered by the mnemonic CLOT:

  • —Clot: recurrent arterial and/or venous thrombosis (clots).
  • —Livedo reticularis: lace-like rash over the extremities and trunk exaggerated by cold conditions.
  • —Obstetrical complications: recurrent fetal loss, placental ischemic conditions (preeclampsia, intrauterine growth restriction).
  • —Thrombocytopenia.
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