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Where do the spinothalamic fibers decussate?
These fibers decussate at the level they enter the spinal cord, after synapsing in Rexed’s lamina II (substantia gelatinosa).
At what locations do they synapse?
They also synapse in the VPL of the thalamus before going to the cortex.
What types of receptors are stimulated to sense this information?
Pain and temperature are perceived by naked terminals of A delta and C fibers and by many specialized chemoreceptors that are excited by tissue substances released in response to noxious and inflammatory stimuli.
Substance P is thought to be the neurotransmitter released by A delta and C fibers at their connections with the interneurons in the spinal cord.
