What radiographic features in the knee suggest CPPD rather than typical primary OA?
The knee is the most common joint involved in CPPD. Certain radiographic features help in separating OA with CPPD from OA. In primary OA, the medial compartment of the knee is more commonly involved, resulting in varus changes. OA with CPPD is more likely to affect the lateral compartment, causing bilateral or unilateral valgus changes. Isolated patellofemoral OA, bilateral involvement, exuberant osteophytosis , and flexion contractures are also more common in OA with CPPD than in primary OA.