What molecular alterations lead to neurological disease or affect management/prognosis?

What molecular alterations lead to neurological disease or affect management/prognosis?

  • Excitation–contraction uncoupling (e.g., channelopathies)
  • Dysfunctional volume regulation (e.g., cytotoxic edema)
  • Altered membrane excitability (e.g., epilepsy)
  • Conduction abnormalities (e.g., demyelinating conditions)
  • Oxidative stress (e.g., mitochondrial disorders)
  • Autoimmune attack of receptors (e.g., myasthenia gravis)
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