What is remission in nephrotic syndrome
Typically, patients with nephrotic syndrome are taught to monitor their urine protein at home using dipsticks.
A complete remission is defined in children as a urine dipstick of trace to negative or a urine protein/creatinine ratio of <0.2. In adults, a complete remission is defined as a reduction of proteinuria to ≤300 mg of urinary protein in a 24-hour period; however, a urine protein-to-creatinine ratio of <0.2 is also an appropriate benchmark for adults.
A partial remission is defined as a ≥50% reduction in 24-hour protein or a 24-hour urine protein of <3.5 g with a normal serum albumin.
Patients with MCD almost always experience a complete, as opposed to a partial, remission. Normalization of serum albumin quickly follows the reduction in proteinuria, but hyperlipidemia may take several months to resolve.
