Target organs involved in Relapsing Polychondritis
Which target organs are most commonly involved in the clinical presentation and eventual course of RPC?
| Clinical Features of RPC a | ||
|---|---|---|
| Clinical Feature | Frequency at Presentation (%) | Cumulative Frequency (%) |
| Auricular chondritis | 43 | 89 |
| Arthritis | 32 | 72 |
| Nasal chondritis | 21 | 61 |
| Ocular inflammation | 18 | 59 |
| Laryngotracheal symptoms | 23 | 55 |
| Reduced hearing | 7 | 40 |
| Vestibular dysfunction | 4 | 28 |
| Saddle nose | 11 | 25 |
| Cutaneous | 4 | 25 |
| Laryngotracheal stricture | 15 | 23 |
| Vasculitis | 2 | 14 |
A large cohort study from the Mayo Clinic has demonstrated that 85% of patients experience episodic attacks of inflammation approximately once annually; the remaining 15% experience continuous disease activity.
a Data from Kent PD, Michet CJ, Luthra HS. Curr Opin Rheumatol . 2004;16:56–61.
