Should elderly patients be classified as CKD even though there is an expected decline in GFR with aging?
The normal GFR in young adults is approximately 125 mL/min per 1.73 m 2 . GFR declines with age, with the mean GFR being 65 mL/min per m 2 at ages 80 to 89 years.
Other studies have demonstrated a decline in GFR ranging from 6 to 12 mL/min per 1.73 m 2 per decade of age.
Increased ACR also occurs with aging. There has been controversy as to whether a decreased eGFR or increased ACR is a disease or part of normal aging.
Since these abnormalities are associated with adverse outcomes, these people should be classified as having CKD.