Rheumatologic Disease Associated with Pouchitis and Microscopic Colitis
Pouchitis | LC | CC | |
|---|---|---|---|
| Peripheral SpA | Yes | Yes | Yes (10%) |
| Axial SpA | No | Yes a | No |
| Rheumatoid arthritis | No | Yes | Yes |
| Thyroiditis/other autoimmune disease | No | Yes | Yes |
a Up to 60% of patients with ankylosing spondylitis have asymptomatic microscopic colitis/Crohn’s-like lesions on right-sided colon biopsies. However, only 6%–10% will evolve into overt IBD.

