Resuscitation strategies on the incidence of acute kidney injury in septic shock
What is the role of resuscitation strategies on the incidence of acute kidney injury in patients with septic shock?
In the ProCESS trial, the development of acute kidney injury was common (approximately 38%) and was not influenced by protocolized resuscitation compared with usual care.
Furthermore, the duration of acute kidney injury and the need for dialysis did not differ between the protocolized care and usual care groups.
Of note, 60-day hospital mortality was 6.2% for patients without acute kidney injury, 16.8% for those with stage 1, and 27.7% for stages 2 to 3.
Thus, while acute kidney injury is common in patients with septic shock and is associated with significant mortality, its rates and outcomes do not appear to be influenced by resuscitation protocols.
