What are the neurologic complications of hemophilia?
Intracranial hemorrhages of multiple types are the most serious consequence of factor VIII deficiency.
A history of head trauma is often obtained, preceding symptoms of a subdural hemorrhage by days.
Subarachnoid and intraparenchymal hemorrhages cause more rapid progression of symptoms and carry an increased risk for mortality.
Intraspinal hemorrhage, while rare, rapidly produces cord compression and paralysis, while soft tissue hematomas may cause focal compressive neuropathies.