Is turmeric good for rheumatic arthritis
The use of curcumin, the principal active component in turmeric, dates back >4000 years in cuisine and religious ceremonies in India; it was later adopted in Ayurvedic medicine. The mechanisms by which it has been shown to attenuate the immune system are mainly via antioxidative and antiinflammatory actions. Turmeric is used to treat OA pain by depleting substance P from nerve root endings similar to capsaicin. There have been small RCTs in the recent years that have reported its benefit in patient populations with RA and lupus nephritis, resulting in reports of improved disease activity, decreased proteinuria, improved BP control, and decreased hematuria. However, these preliminary studies have small sample sizes. In 2017, Nelson et al. questioned the efficacy of this agent due to its low bioavailability and unstable, reactive nature. I usually tell my patients that it is safe to consume at recommended doses (recommended therapeutic dose is 400–600 mg three times a day), along with the conventional DMARD or biologic therapy they have been prescribed.