What disorders and infections are associated with inflammatory diarrhea?
Inflammatory diarrhea is generally associated with disorders that cause mucosal disruption. Mucosal compromise may be due to a primary (IBD) or secondary (invasive infectious organism) process. Invasive infectious agents associated with diarrhea include Salmonella, Shigella, Campylobacter, enterohemorrhagic E. coli (EHEC; O157:H7), enteroinvasive E. coli, and other Shiga toxin–producing E. coli (STEC), C. difficile, E. histolytica, and Yersinia enterocolitica. Noninfectious causes of inflammatory diarrhea include ulcerative colitis, Crohn’s disease, radiation enteritis, ischemic and vascular diseases, and diverticulitis.