Inflammatory diarrhea

What disorders and infections are associated with inflammatory diarrhea? 

  • Inflammatory diarrhea is generally associated with disorders that cause mucosal disruption.
  • Mucosal compromise may be due to a primary (IBD) or secondary (invasive infectious organism) process. Invasive infectious agents associated with diarrhea include Salmonella, Shigella, Campylobacter, enterohemorrhagic E. coli (EHEC; O157:H7), enteroinvasive E. coli, and other Shiga toxin–producing E. coli (STEC), C. difficile, E. histolytica, and Yersinia enterocolitica. 
  • Noninfectious causes of inflammatory diarrhea include ulcerative colitis, Crohn’s disease, radiation enteritis, ischemic and vascular diseases, and diverticulitis.
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