How to diagnose suspected Alzheimers Disease

How to diagnose suspected Alzheimers Disease

Which blood tests are typically ordered in a patient with suspected Alzheimers Disease to rule out other causes or contributing factors?

  • Comprehensive metabolic panel (including sodium, blood sugar, calcium, liver enzymes, and renal function)
  • Complete blood count with differential
  • Thyroid function tests
  • Rapid plasma reagin or equivalent test for syphilis
  • Vitamin B12
  • Antinuclear antibody (extractable nuclear antigen panel, if positive)
  • Sedimentation rate

Additional tests:

  • Folate
  • Serum homocysteine
  • Serum methylmalonic acid
  • Serum arterial ammonia
  • Parathyroid hormone
  • Serum protein electrophoresis
  • Cortisol levels
  • Serum (and urine) drug screens
  • Hexosaminidase levels
  • HIV
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