How does uveitis present differently depending on the associated SpA?
Ankylosing spondylitis and reactive arthritis: About 90% are HLA-B27-positive, and men are affected more often than women. Typically sudden onset of anterior uveitis that is unilateral but alternating has a recurrent course and usually resolves completely within several months.
PsA and enteropathic: patients who are HLA-B27-positive (45%–60%) may present with classic AAU. However, patients who are HLA-B27-negative may present with the insidious onset of bilateral, chronic uveitis that may be anterior, intermediate, or posterior in location.
