How does amyloid deposition result in clinical disease
Why is it called amyloid? How does its deposition result in clinical disease?
In 1854, Rudolph Virchow coined the term amyloid (starch-like) owing to the reaction of the material in a manner similar to cellulose when exposed to iodine and sulfuric acid. This designation has been retained despite the recognition of the proteinaceous nature of amyloid. Amyloid deposits encroach on parenchymal tissues, compromising their function. Organ compromise is related to the location, quantity, and rate of deposition which varies within and between the types of amyloid.
