Histologically, what findings suggest peptic duodenitis?
- Gastric foveolar metaplasia is seen in the villi (which may be focal or extensive), along with active lesions (i.e., cryptitis or crypt abscess) and increased chronic inflammation in the lamina propria. Rarely, Helicobacter organisms may be identified in cases with extensive foveolar metaplasia. The differential diagnosis includes gastric heterotopia.
