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Grossly expansile lucent bone lesion
Most common
- 1. Plasmacytoma —older patients, usually in axial or proximal appendicular skeleton.
- 2. Metastases —RCC, thyroid, HCC, phaeochromocytoma, melanoma. Usually in axial or proximal appendicular skeleton.
- 3. Aneurysmal bone cyst —in children and young adults. Usually has a thin sclerotic margin.
- 4. Giant cell tumour —usually older patients than ABC. Often abuts articular surface, no sclerotic margin.
Less common
- 5. Telangiectatic osteosarcoma —mimics ABC.
- 6. Fibrous dysplasia —usually fusiform expansion rather than a discrete expansile mass.
- 7. Brown tumour —look for other signs of hyperparathyroidism.
- 8. Haemangioma —often expansile when in flat bones, e.g. skull or pelvis, with a sunburst periosteal reaction.
- 9. Chordoma —in sacrum, clivus or vertebral bodies.
Rare
- 10. Haemophilic pseudotumour —look for other signs of haemophilia.
- 11. Slow growing central bone sarcoma.
- 12. Hydatid cyst.