What enteric pathogens are associated with reactive arthritis?
- Several enteric bacterial pathogens may be associated with postinfectious autoimmune arthritis syndromes.
- Salmonella, Yersinia, Campylobacter, and Shigella are most commonly associated. More recently, E. coli and C. difficile infection have been associated with arthralgia or arthritis syndromes as well.
- In addition to asymmetric oligoarthritis, some patients may develop conjunctivitis or skin eruptions (keratoderma blennorrhagica or erythema nodosum).
- Management includes the treatment of the inciting infection and then judicious use of antiinflammatory therapies (nonsteroidal antiinflammatory drugs, disease-modifying antirheumatic drugs, steroids).