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Differential diagnosis of aphthous stomatitis
Underlying conditions may be identified in as many as 30% of patients with severe aphthous stomatitis. However, most cases remain idiopathic
Differential Diagnosis of Recurrent Oral Ulcerations
| Condition | Condition |
|---|---|
| Idiopathic (70% of cases) | Dermatologic Dz: pemphigoid, pemphigus, lichen planus, others |
| B 12 /folate/iron deficiency | Autoinflammatory Dz: PFAPA, Hyperimmunoglobulin D |
| Cyclic neutropenia | Drugs (e.g., methotrexate) |
| Menstrual-related | Infections: herpes simplex, HIV |
| Recurrent (complex) aphthosis | Stevens-Johnson syndrome |
| Inflammatory bowel disease | Gluten-sensitive enteropathy (Celiac Dz) |
| Behçet’s disease | Rheumatologic Dz: SLE, reactive arthritis |
