Can Multiple Sclerosis be diagnosed after only one attack of symptoms?
Multiple Sclerosis may begin in some patients as a clinically isolated syndrome such as a single, monophasic episode of optic neuritis or transverse myelitis.
If this patient has an MRI showing dissemination in space (i.e., subclinical disease in another location in the central nervous system), and the lesions are disseminated in time (i.e., some enhance and some do not), then a diagnosis of Multiple Sclerosis can be made.
