Best treatment for urologic problems in Multiple Sclerosis

What is the best treatment for urologic problems in Multiple Sclerosis? 

Urologic consultation is often useful to manage the neurogenic bladder.

The most common problem is a hyperreflexic bladder with a small capacity, early detrusor contraction, urinary frequency, and urgency.

It can be managed with medications such as oxybutynin (Ditropan), tolterodine (Detrol), or hyoscyamine (Levsinex).

A flaccid bladder (more rare) may require self-catheterization.

When sphincter–detrusor dyssynergia appears, medications to relax the sphincter, such as the alpha-adrenergic blocking agent prazosin (Minipress), may be useful.

Sources

Lapierre Y, Hum S: Treating fatigue. Int MS J 14:64-71, 2007.

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